Capillary electrophoresis-electrochemistry microfluidic system for the determination of organic peroxides

Joseph Wang, Alberto Escarpa, Martin Pumera, Jason Feldman

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

A microfluidic analytical system for the separation and detection of organic peroxides, based on a microchip capillary electrophoresis device with an integrated amperometric detector, was developed. The new microsystem relies on the reductive detection of both organic acid peroxides and hydroperoxides at -700 mV (vs. Ag wire/AgCl). Factors influencing the separation and detection processes were examined and optimized. The integrated microsystem offers rapid measurements (within 130 s) of these organic-peroxide compounds, down to micromolar levels. A highly stable response for repetitive injections (RSD 0.35-3.12%; n=12) reflects the negligible electrode passivation. Such a "lab-on-a-chip" device should be attractive for on-site analysis of organic peroxides, as desired for environmental screening and industrial monitoring.

Original languageEnglish
Pages (from-to)249-254
Number of pages6
JournalJournal of Chromatography A
Volume952
Issue number1-2
DOIs
Publication statusPublished - 2002 Apr 5

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Capillary electrophoresis-electrochemistry microfluidic system for the determination of organic peroxides'. Together they form a unique fingerprint.

  • Cite this