We have fabricated carbon nanotube (CNT)-based biosensor with a field-effect transistor structure for detection of hepatitis B. For real-time measurement, a microfluidic channel was mounted on the device and the presence of hepatitis B antigen was detected by measuring the electrical conductance as a function of time. When hepatitis B antigen was exposed to the CNT biosensor with hepatitis B antibody immobilized, the conductance increased and then became nearly constant within 10 min. As the antigen concentration increases, the conductance increased further. These results demonstrate that hepatitis B is possibly detected in real-time using the CNT biosensor.
Bibliographical noteFunding Information:
This work has been financially supported by Korea Science and Engineering Foundation through National Core Research Center for Nanomedical Technology (Grant No. R15-20040924-00000-0).
All Science Journal Classification (ASJC) codes
- Materials Science(all)
- Physics and Astronomy(all)