Cardiac 123I-MIBG scintigraphy in patients with essential tremor

philhyu Lee, Ji Woo Kim, Oh Young Bang, In Soo Joo, Seok Nam Yoon, Kyoon Huh

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of 123I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.

Original languageEnglish
Pages (from-to)1235-1238
Number of pages4
JournalMovement Disorders
Volume21
Issue number8
DOIs
Publication statusPublished - 2006 Aug 1

Fingerprint

Essential Tremor
Radionuclide Imaging
Parkinson Disease
Tremor
Myocardial Perfusion Imaging
Mediastinum

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Lee, P., Kim, J. W., Bang, O. Y., Joo, I. S., Yoon, S. N., & Huh, K. (2006). Cardiac 123I-MIBG scintigraphy in patients with essential tremor. Movement Disorders, 21(8), 1235-1238. https://doi.org/10.1002/mds.20908
Lee, philhyu ; Kim, Ji Woo ; Bang, Oh Young ; Joo, In Soo ; Yoon, Seok Nam ; Huh, Kyoon. / Cardiac 123I-MIBG scintigraphy in patients with essential tremor. In: Movement Disorders. 2006 ; Vol. 21, No. 8. pp. 1235-1238.
@article{0644927f91184897941788d35f2ad18d,
title = "Cardiac 123I-MIBG scintigraphy in patients with essential tremor",
abstract = "In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of 123I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.",
author = "philhyu Lee and Kim, {Ji Woo} and Bang, {Oh Young} and Joo, {In Soo} and Yoon, {Seok Nam} and Kyoon Huh",
year = "2006",
month = "8",
day = "1",
doi = "10.1002/mds.20908",
language = "English",
volume = "21",
pages = "1235--1238",
journal = "Movement Disorders",
issn = "0885-3185",
publisher = "John Wiley and Sons Inc.",
number = "8",

}

Lee, P, Kim, JW, Bang, OY, Joo, IS, Yoon, SN & Huh, K 2006, 'Cardiac 123I-MIBG scintigraphy in patients with essential tremor', Movement Disorders, vol. 21, no. 8, pp. 1235-1238. https://doi.org/10.1002/mds.20908

Cardiac 123I-MIBG scintigraphy in patients with essential tremor. / Lee, philhyu; Kim, Ji Woo; Bang, Oh Young; Joo, In Soo; Yoon, Seok Nam; Huh, Kyoon.

In: Movement Disorders, Vol. 21, No. 8, 01.08.2006, p. 1235-1238.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Cardiac 123I-MIBG scintigraphy in patients with essential tremor

AU - Lee, philhyu

AU - Kim, Ji Woo

AU - Bang, Oh Young

AU - Joo, In Soo

AU - Yoon, Seok Nam

AU - Huh, Kyoon

PY - 2006/8/1

Y1 - 2006/8/1

N2 - In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of 123I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.

AB - In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of 123I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.

UR - http://www.scopus.com/inward/record.url?scp=33748374485&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748374485&partnerID=8YFLogxK

U2 - 10.1002/mds.20908

DO - 10.1002/mds.20908

M3 - Article

C2 - 16671077

AN - SCOPUS:33748374485

VL - 21

SP - 1235

EP - 1238

JO - Movement Disorders

JF - Movement Disorders

SN - 0885-3185

IS - 8

ER -