Cardiosulfa, a small molecule that induces abnormal heart development in zebrafish, and its biological implications

Sung Kyun Ko, Hui Juan Jin, Da Woon Jung, Xizhe Tian, Injae Shin

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A change of heart: Cardiosulfa, a small molecule that induces heart deformation during zebrafish development, has been identified by using a forward chemicalgenetic approach. Zebrafish embryos exposed to cardiosulfa have a narrow and elongated heart within an enlarged pericardial sac (see picture; heart marked with green fluorescent protein).

Original languageEnglish
Pages (from-to)7809-7812
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number42
DOIs
Publication statusPublished - 2009 Oct 5

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Molecules
Green Fluorescent Proteins
Proteins
cardiosulfa

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Cite this

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Cardiosulfa, a small molecule that induces abnormal heart development in zebrafish, and its biological implications. / Ko, Sung Kyun; Jin, Hui Juan; Jung, Da Woon; Tian, Xizhe; Shin, Injae.

In: Angewandte Chemie - International Edition, Vol. 48, No. 42, 05.10.2009, p. 7809-7812.

Research output: Contribution to journalArticle

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