Cardiovascular disease and cardiovascular disease risk in HIV-positive populations in the Asian region

Rimke Bijker, Jun Yong Choi, Rossana Ditangco, Sasisopin Kiertiburanakul, Man Po Lee, Sarawut Siwamogsatham, Sanjay Pujari, Jeremy Ross, Chi Yuen Wong, Wing Wai Wong, Evy Yunihastuti, Matthew Law

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Introduction: Cardiovascular diseases (CVD) are becoming more prevalent in HIV-infected populations as they age largely due to improved treatment outcomes. Assessment of CVD risk and CVD risk factors in HIV-positive populations has focused on high income settings, while there are limited studies evaluating CVD in HIV-positive populations in the Asian region. Materials and Methods: We provided an overview of the prevalence and incidence of CVD and its risk factors in adult HIV-positive populations, and of the strategies currently in place for CVD management in the Asian region. Results: Studies from the Asian region showed that CVD and CVD risk factors, such as dyslipidaemia, elevated blood glucose, obesity and smoking, are highly prevalent in HIV-positive populations. A number of studies suggested that HIV infection and antiretroviral therapy may contribute to increased CVD risk. National HIV treatment guidelines provide some directions regarding CVD risk prevention and management in the HIV-infected population, however, they are limited in number and scope. Conclusion: Development and consolidation of guidelines for integrated CVD and HIV care are essential to control the burden of CVD in HIVpositive populations. To inform guidelines, policies and practice in the Asian region, research should focus on exploring appropriate CVD risk screening strategies and estimating current and future CVD mortality and morbidity rates.

Original languageEnglish
Pages (from-to)52-66
Number of pages15
JournalOpen AIDS Journal
Volume11
DOIs
Publication statusPublished - 2017 Aug 1

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Virology

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    Bijker, R., Choi, J. Y., Ditangco, R., Kiertiburanakul, S., Lee, M. P., Siwamogsatham, S., Pujari, S., Ross, J., Wong, C. Y., Wong, W. W., Yunihastuti, E., & Law, M. (2017). Cardiovascular disease and cardiovascular disease risk in HIV-positive populations in the Asian region. Open AIDS Journal, 11, 52-66. https://doi.org/10.2174/1874613601711010052