Carmustine induces ERK- and JNK-dependent cell death of neuronally-differentiated PC12 cells via generation of reactive oxygen species

Pharmacology, Toxicology and Pharmaceutical Science

• Acetylcysteine 8%
• Antioxidant 8%
• Carmustine 100%
• Caspase 3 33%
• Cell Death 58%
• Cytotoxicity 8%
• Glutathione 8%
• Glutathione Reductase 16%
• Mitogen Activated Protein Kinase 66%
• Neurotoxicity 8%
• Phosphotransferase 41%
• Protein Kinase C 8%
• Reactive Oxygen Metabolite 41%
• Reducing Agent 8%

Neuroscience

• Acetylcysteine 8%
• Amino Terminal Sequence 33%
• Antioxidant 8%
• Carmustine 83%
• Caspase 3 33%
• Cytotoxicity 8%
• Extracellular Signal-Regulated Kinases 33%
• Glutathione 8%
• Glutathione Reductase 16%
• Kinase 41%
• Mitogen-Activated Protein Kinase 33%
• Neurotoxicity 8%
• Phosphorylation 8%
• Reactive Oxygen Species 41%