Cell microarray technologies for high-throughput cell-based biosensors

Hye Jin Hong, Woong Sub Koom, Won Gun Koh

Research output: Contribution to journalReview article

16 Citations (Scopus)

Abstract

Due to the recent demand for high-throughput cellular assays, a lot of efforts have been made on miniaturization of cell-based biosensors by preparing cell microarrays. Various microfabrication technologies have been used to generate cell microarrays, where cells of different phenotypes are immobilized either on a flat substrate (positional array) or on particles (solution or suspension array) to achieve multiplexed and high-throughput cell-based biosensing. After introducing the fabrication methods for preparation of the positional and suspension cell microarrays, this review discusses the applications of the cell microarray including toxicology, drug discovery and detection of toxic agents.

Original languageEnglish
Article number1293
JournalSensors (Switzerland)
Volume17
Issue number6
DOIs
Publication statusPublished - 2017 Jun 5

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Electrical and Electronic Engineering

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