Central retinal vein occlusion associated with ulcerative colitis

Yuri Seo, Min Kim, Jin Hyoung Kim, Jae Jun Park, Sungchul Lee

Research output: Contribution to journalArticle

Abstract

Purpose To report a case of central retinal vein occlusion without macular edema associated with ulcerative colitis and its novel treatment with intravitreal dexamethasone. Case Report A 40-year-old man with ulcerative colitis presented with sudden visual disturbances. An initial fundus examination showed subtle yellow-to-white patches within the inner retina of the right eye superotemporal to the fovea. There were intraretinal hemorrhages and cotton-wool spots within the superior vascular arcade and nasal to the optic disc. Despite initiation of systemic corticosteroids, 2 weeks later there was an increase in retinal hemorrhages, formation of cotton wool spots, and development of optic disc swelling in the right eye. The patient was eventually diagnosed with nonischemic central retinal vein occlusion associated with ulcerative colitis. He received sustained-release intravitreal dexamethasone, which led to the resolution of retinal hemorrhage, optic disc swelling, and cotton-wool spots. Three months after the injection, retinal hemorrhages were not detectable. However, ocular coherence imaging showed marked thinning of the inner retina at the locations that were previously hyper-reflective. Conclusions Central retinal vein occlusion is an uncommon ophthalmologic manifestation associated with ulcerative colitis. Injection of intravitreal dexamethasone could be a viable treatment option in these patients even without the presence of macular edema.

Original languageEnglish
Pages (from-to)1567-1570
Number of pages4
JournalOptometry and Vision Science
Volume93
Issue number12
DOIs
Publication statusPublished - 2016 Dec 1

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Retinal Vein
Retinal Vein Occlusion
Retinal Hemorrhage
Ulcerative Colitis
Wool
Optic Disk
Dexamethasone
Macular Edema
Retina
Intravitreal Injections
Nose
Blood Vessels
Adrenal Cortex Hormones
Hemorrhage
Injections
Therapeutics

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Optometry

Cite this

Seo, Yuri ; Kim, Min ; Kim, Jin Hyoung ; Park, Jae Jun ; Lee, Sungchul. / Central retinal vein occlusion associated with ulcerative colitis. In: Optometry and Vision Science. 2016 ; Vol. 93, No. 12. pp. 1567-1570.
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Central retinal vein occlusion associated with ulcerative colitis. / Seo, Yuri; Kim, Min; Kim, Jin Hyoung; Park, Jae Jun; Lee, Sungchul.

In: Optometry and Vision Science, Vol. 93, No. 12, 01.12.2016, p. 1567-1570.

Research output: Contribution to journalArticle

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