Central serous chorioretinopathy after renal transplantation

Christopher Seungkyu Lee, Eui Chun Kang, Kyu Sung Lee, Seok Ho Byeon, Hyoung Jun Koh, Sungchul Lee

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Purpose: To describe the demographic and clinical characteristics of central serous chorioretinopathy (CSC) after renal transplantation (RT). Methods: A retrospective medical chart review was performed on 451 among 2,980 patients, who underwent RT and visited vitreoretinal clinic at Yonsei Medical Center from 1979 to 2009. Correlation between daily corticosteroid dosage and remission time and factors relating to final visual acuity of <20/40 were studied. Results: Twenty-eight patients (39 eyes) developed CSC at a median of 63 months after RT (range, 2 months to 20 years), and 18 (64%) patients were men. Accordingly, the prevalence of CSC after RT was estimated to be between 1% and 6%. All patients received a combination of corticosteroid and at least one other immunosuppressant agent at presentation. Reducing the daily corticosteroid dosage by 25% to 50% in CSC with classic pattern resulted in twice as faster remission (2 months) compared with the maintained dosage group (P = 0.025). Central serous chorioretinopathy recurrence (P = 0.002), intrinsic renal disease as cause of RT (P = 0.003), severe CSC variant (P = 0.009), and presenting visual acuity <20/40 (P = 0.009) predicted a final visual acuity <20/40. Conclusion: Central serous chorioretinopathy develops relatively often after RT and varies in presentation and severity. The cause of CSC after RT appears to be multifactorial and closely related to corticosteroid.

Original languageEnglish
Pages (from-to)1896-1903
Number of pages8
JournalRetina
Volume31
Issue number9
DOIs
Publication statusPublished - 2011 Oct 1

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Central Serous Chorioretinopathy
Kidney Transplantation
Adrenal Cortex Hormones
Visual Acuity
Immunosuppressive Agents
Demography
Kidney
Recurrence

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Lee, C. S., Kang, E. C., Lee, K. S., Byeon, S. H., Koh, H. J., & Lee, S. (2011). Central serous chorioretinopathy after renal transplantation. Retina, 31(9), 1896-1903. https://doi.org/10.1097/IAE.0b013e31820a69ee
Lee, Christopher Seungkyu ; Kang, Eui Chun ; Lee, Kyu Sung ; Byeon, Seok Ho ; Koh, Hyoung Jun ; Lee, Sungchul. / Central serous chorioretinopathy after renal transplantation. In: Retina. 2011 ; Vol. 31, No. 9. pp. 1896-1903.
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Lee, CS, Kang, EC, Lee, KS, Byeon, SH, Koh, HJ & Lee, S 2011, 'Central serous chorioretinopathy after renal transplantation', Retina, vol. 31, no. 9, pp. 1896-1903. https://doi.org/10.1097/IAE.0b013e31820a69ee

Central serous chorioretinopathy after renal transplantation. / Lee, Christopher Seungkyu; Kang, Eui Chun; Lee, Kyu Sung; Byeon, Seok Ho; Koh, Hyoung Jun; Lee, Sungchul.

In: Retina, Vol. 31, No. 9, 01.10.2011, p. 1896-1903.

Research output: Contribution to journalArticle

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T1 - Central serous chorioretinopathy after renal transplantation

AU - Lee, Christopher Seungkyu

AU - Kang, Eui Chun

AU - Lee, Kyu Sung

AU - Byeon, Seok Ho

AU - Koh, Hyoung Jun

AU - Lee, Sungchul

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N2 - Purpose: To describe the demographic and clinical characteristics of central serous chorioretinopathy (CSC) after renal transplantation (RT). Methods: A retrospective medical chart review was performed on 451 among 2,980 patients, who underwent RT and visited vitreoretinal clinic at Yonsei Medical Center from 1979 to 2009. Correlation between daily corticosteroid dosage and remission time and factors relating to final visual acuity of <20/40 were studied. Results: Twenty-eight patients (39 eyes) developed CSC at a median of 63 months after RT (range, 2 months to 20 years), and 18 (64%) patients were men. Accordingly, the prevalence of CSC after RT was estimated to be between 1% and 6%. All patients received a combination of corticosteroid and at least one other immunosuppressant agent at presentation. Reducing the daily corticosteroid dosage by 25% to 50% in CSC with classic pattern resulted in twice as faster remission (2 months) compared with the maintained dosage group (P = 0.025). Central serous chorioretinopathy recurrence (P = 0.002), intrinsic renal disease as cause of RT (P = 0.003), severe CSC variant (P = 0.009), and presenting visual acuity <20/40 (P = 0.009) predicted a final visual acuity <20/40. Conclusion: Central serous chorioretinopathy develops relatively often after RT and varies in presentation and severity. The cause of CSC after RT appears to be multifactorial and closely related to corticosteroid.

AB - Purpose: To describe the demographic and clinical characteristics of central serous chorioretinopathy (CSC) after renal transplantation (RT). Methods: A retrospective medical chart review was performed on 451 among 2,980 patients, who underwent RT and visited vitreoretinal clinic at Yonsei Medical Center from 1979 to 2009. Correlation between daily corticosteroid dosage and remission time and factors relating to final visual acuity of <20/40 were studied. Results: Twenty-eight patients (39 eyes) developed CSC at a median of 63 months after RT (range, 2 months to 20 years), and 18 (64%) patients were men. Accordingly, the prevalence of CSC after RT was estimated to be between 1% and 6%. All patients received a combination of corticosteroid and at least one other immunosuppressant agent at presentation. Reducing the daily corticosteroid dosage by 25% to 50% in CSC with classic pattern resulted in twice as faster remission (2 months) compared with the maintained dosage group (P = 0.025). Central serous chorioretinopathy recurrence (P = 0.002), intrinsic renal disease as cause of RT (P = 0.003), severe CSC variant (P = 0.009), and presenting visual acuity <20/40 (P = 0.009) predicted a final visual acuity <20/40. Conclusion: Central serous chorioretinopathy develops relatively often after RT and varies in presentation and severity. The cause of CSC after RT appears to be multifactorial and closely related to corticosteroid.

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