TY - JOUR
T1 - Ceramic bioactivity
T2 - Progresses, challenges and perspectives
AU - Lee, K. Y.
AU - Park, M.
AU - Kim, H. M.
AU - Lim, Y. J.
AU - Chun, H. J.
AU - Kim, H.
AU - Moon, S. H.
PY - 2006/6/1
Y1 - 2006/6/1
N2 - Bioactivity is a property of the ceramic surface which induces biological integration of living soft and hard tissues. The core mechanism of bioactivity is surface biomineralization of calcium phosphate nanocrystallites on ceramics with specific compositions and structures, inspiring acellular and cellular strategies for bio-interactive materials with new physical, chemical and biological functions. These include bioactive surface functionalizations on metallic, ceramic and polymeric substrata for biomedical materials with different mechanical properties, bioactive ceramic-polymer nanohybrids for soft tissue replacements and engineering, template-textured depositions of biomimetic nano-calcium phosphate for hybridization of bio-macromolecular and cellular functions, concerning which this paper reviews with in vivo and in vitro fundamentals and perspectives in tissue engineering.
AB - Bioactivity is a property of the ceramic surface which induces biological integration of living soft and hard tissues. The core mechanism of bioactivity is surface biomineralization of calcium phosphate nanocrystallites on ceramics with specific compositions and structures, inspiring acellular and cellular strategies for bio-interactive materials with new physical, chemical and biological functions. These include bioactive surface functionalizations on metallic, ceramic and polymeric substrata for biomedical materials with different mechanical properties, bioactive ceramic-polymer nanohybrids for soft tissue replacements and engineering, template-textured depositions of biomimetic nano-calcium phosphate for hybridization of bio-macromolecular and cellular functions, concerning which this paper reviews with in vivo and in vitro fundamentals and perspectives in tissue engineering.
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U2 - 10.1088/1748-6041/1/2/R01
DO - 10.1088/1748-6041/1/2/R01
M3 - Review article
C2 - 18460754
AN - SCOPUS:33745668682
SN - 1748-6041
VL - 1
SP - R31-R37
JO - Biomedical Materials (Bristol)
JF - Biomedical Materials (Bristol)
IS - 2
M1 - R01
ER -