Cervical cancer associated with pregnancy

Results of a multicenter retrospective Korean study (KGOG-1006)

Jong Min Lee, Kwang Beom Lee, Young Tak Kim, Hee Sug Ryu, YoungTae Kim, Chi Heum Cho, Sung Eun Namkoong, Ki Hun Lee, Ho Sun Choi, Kyung Tai Kim

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Objective: The objective of the study was to analyze the characteristics of cervical cancer associated with pregnancy. Study Design: Forty patients with cervical cancer associated with pregnancy were retrospectively identified between 1995-2003. Three controls for each case were matched on the basis of age, stage, histology, and date of treatment. Results: Sampling of cervical cytology after the second trimester was the most common cause of delayed diagnosis. Among 12 patients who delayed treatment for fetal maturity, 2 died of disease. There was no difference in overall survival between pregnant and nonpregnant patients with stage Ib tumors. In contrast to nonpregnant patients, the depth of stromal invasion was not correlated with the incidence of lymph vascular space involvement and lymph node metastasis in pregnant patients. Conclusion: Thorough evaluation is warranted before deciding whether to delay treatment until fetal maturity. Pregnancy does not adversely affect the prognosis of early-stage cervical cancer significantly.

Original languageEnglish
Pages (from-to)92.e1-92.e6
JournalAmerican Journal of Obstetrics and Gynecology
Volume198
Issue number1
DOIs
Publication statusPublished - 2008 Jan 1

Fingerprint

Uterine Cervical Neoplasms
Retrospective Studies
Pregnancy
Delayed Diagnosis
Second Pregnancy Trimester
Lymph
Blood Vessels
Cell Biology
Histology
Therapeutics
Lymph Nodes
Neoplasm Metastasis
Survival
Incidence
Neoplasms

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

Cite this

Lee, Jong Min ; Lee, Kwang Beom ; Kim, Young Tak ; Ryu, Hee Sug ; Kim, YoungTae ; Cho, Chi Heum ; Namkoong, Sung Eun ; Lee, Ki Hun ; Choi, Ho Sun ; Kim, Kyung Tai. / Cervical cancer associated with pregnancy : Results of a multicenter retrospective Korean study (KGOG-1006). In: American Journal of Obstetrics and Gynecology. 2008 ; Vol. 198, No. 1. pp. 92.e1-92.e6.
@article{c82ec20fb14545718eee1d7d8e951f6f,
title = "Cervical cancer associated with pregnancy: Results of a multicenter retrospective Korean study (KGOG-1006)",
abstract = "Objective: The objective of the study was to analyze the characteristics of cervical cancer associated with pregnancy. Study Design: Forty patients with cervical cancer associated with pregnancy were retrospectively identified between 1995-2003. Three controls for each case were matched on the basis of age, stage, histology, and date of treatment. Results: Sampling of cervical cytology after the second trimester was the most common cause of delayed diagnosis. Among 12 patients who delayed treatment for fetal maturity, 2 died of disease. There was no difference in overall survival between pregnant and nonpregnant patients with stage Ib tumors. In contrast to nonpregnant patients, the depth of stromal invasion was not correlated with the incidence of lymph vascular space involvement and lymph node metastasis in pregnant patients. Conclusion: Thorough evaluation is warranted before deciding whether to delay treatment until fetal maturity. Pregnancy does not adversely affect the prognosis of early-stage cervical cancer significantly.",
author = "Lee, {Jong Min} and Lee, {Kwang Beom} and Kim, {Young Tak} and Ryu, {Hee Sug} and YoungTae Kim and Cho, {Chi Heum} and Namkoong, {Sung Eun} and Lee, {Ki Hun} and Choi, {Ho Sun} and Kim, {Kyung Tai}",
year = "2008",
month = "1",
day = "1",
doi = "10.1016/j.ajog.2007.06.077",
language = "English",
volume = "198",
pages = "92.e1--92.e6",
journal = "American Journal of Obstetrics and Gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "1",

}

Cervical cancer associated with pregnancy : Results of a multicenter retrospective Korean study (KGOG-1006). / Lee, Jong Min; Lee, Kwang Beom; Kim, Young Tak; Ryu, Hee Sug; Kim, YoungTae; Cho, Chi Heum; Namkoong, Sung Eun; Lee, Ki Hun; Choi, Ho Sun; Kim, Kyung Tai.

In: American Journal of Obstetrics and Gynecology, Vol. 198, No. 1, 01.01.2008, p. 92.e1-92.e6.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Cervical cancer associated with pregnancy

T2 - Results of a multicenter retrospective Korean study (KGOG-1006)

AU - Lee, Jong Min

AU - Lee, Kwang Beom

AU - Kim, Young Tak

AU - Ryu, Hee Sug

AU - Kim, YoungTae

AU - Cho, Chi Heum

AU - Namkoong, Sung Eun

AU - Lee, Ki Hun

AU - Choi, Ho Sun

AU - Kim, Kyung Tai

PY - 2008/1/1

Y1 - 2008/1/1

N2 - Objective: The objective of the study was to analyze the characteristics of cervical cancer associated with pregnancy. Study Design: Forty patients with cervical cancer associated with pregnancy were retrospectively identified between 1995-2003. Three controls for each case were matched on the basis of age, stage, histology, and date of treatment. Results: Sampling of cervical cytology after the second trimester was the most common cause of delayed diagnosis. Among 12 patients who delayed treatment for fetal maturity, 2 died of disease. There was no difference in overall survival between pregnant and nonpregnant patients with stage Ib tumors. In contrast to nonpregnant patients, the depth of stromal invasion was not correlated with the incidence of lymph vascular space involvement and lymph node metastasis in pregnant patients. Conclusion: Thorough evaluation is warranted before deciding whether to delay treatment until fetal maturity. Pregnancy does not adversely affect the prognosis of early-stage cervical cancer significantly.

AB - Objective: The objective of the study was to analyze the characteristics of cervical cancer associated with pregnancy. Study Design: Forty patients with cervical cancer associated with pregnancy were retrospectively identified between 1995-2003. Three controls for each case were matched on the basis of age, stage, histology, and date of treatment. Results: Sampling of cervical cytology after the second trimester was the most common cause of delayed diagnosis. Among 12 patients who delayed treatment for fetal maturity, 2 died of disease. There was no difference in overall survival between pregnant and nonpregnant patients with stage Ib tumors. In contrast to nonpregnant patients, the depth of stromal invasion was not correlated with the incidence of lymph vascular space involvement and lymph node metastasis in pregnant patients. Conclusion: Thorough evaluation is warranted before deciding whether to delay treatment until fetal maturity. Pregnancy does not adversely affect the prognosis of early-stage cervical cancer significantly.

UR - http://www.scopus.com/inward/record.url?scp=37349110318&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=37349110318&partnerID=8YFLogxK

U2 - 10.1016/j.ajog.2007.06.077

DO - 10.1016/j.ajog.2007.06.077

M3 - Article

VL - 198

SP - 92.e1-92.e6

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 1

ER -