CHA 2 DS 2 -VASC score in the prediction of ischemic stroke in patients after radiofrequency catheter ablation of typical atrial flutter

Moo Nyun Jin, Changho Song, Tae Hoon Kim, Jae Sun Uhm, Hui Nam Pak, Moon Hyoung Lee, Boyoung Joung

Research output: Contribution to journalArticle

Abstract

Purpose: Despite undergoing successful catheter ablation of typical atrial flutter (AFL), patients remain at increased risk for ischemic stroke. However, data on risk prediction tools for the development of stroke after AFL ablation are lacking. This study investigates whether CHA 2 DS 2 -VASc score is useful for predicting ischemic stroke after successful ablation of typical AFL. Materials and Methods: A total of 293 patients (236 men, mean age 56.1±13.5 years) who underwent successful radiofrequency catheter ablation for typical AFL were included in this study. The clinical end point was occurrence of ischemic stroke during follow-up after AFL ablation. Results: During the follow-up period (60.8±45.9 months), ischemic stroke occurred in 18 (6%) patients at a median of 34 months (interquartile range, 13−65 months). CHA 2 DS 2 -VASc score [hazard ratio 2.104; 95% confidence interval (CI), 1.624−2.726; p<0.001] was an independent predictor for the occurrence of stroke after AFL ablation. The area under the receiver operating characteristic curve for CHA 2 DS 2 -VASc score was 0.798 (95% CI, 0.691−0.904). The CHA 2 DS 2 -VASc score could be used to stratify patients into two groups with different incidences of ischemic stroke (1.6% vs. 14.4%, p<0.001) at a cutoff value of 2. Conclusion: CHA 2 DS 2 -VASc score is useful in a prediction model for the risk of stroke after catheter ablation of typical AFL.

Original languageEnglish
Pages (from-to)236-242
Number of pages7
JournalYonsei medical journal
Volume59
Issue number2
DOIs
Publication statusPublished - 2018 Mar

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Atrial Flutter
Catheter Ablation
Stroke
Confidence Intervals
ROC Curve
Incidence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{cb352cabd25441b7a690322863877a66,
title = "CHA 2 DS 2 -VASC score in the prediction of ischemic stroke in patients after radiofrequency catheter ablation of typical atrial flutter",
abstract = "Purpose: Despite undergoing successful catheter ablation of typical atrial flutter (AFL), patients remain at increased risk for ischemic stroke. However, data on risk prediction tools for the development of stroke after AFL ablation are lacking. This study investigates whether CHA 2 DS 2 -VASc score is useful for predicting ischemic stroke after successful ablation of typical AFL. Materials and Methods: A total of 293 patients (236 men, mean age 56.1±13.5 years) who underwent successful radiofrequency catheter ablation for typical AFL were included in this study. The clinical end point was occurrence of ischemic stroke during follow-up after AFL ablation. Results: During the follow-up period (60.8±45.9 months), ischemic stroke occurred in 18 (6{\%}) patients at a median of 34 months (interquartile range, 13−65 months). CHA 2 DS 2 -VASc score [hazard ratio 2.104; 95{\%} confidence interval (CI), 1.624−2.726; p<0.001] was an independent predictor for the occurrence of stroke after AFL ablation. The area under the receiver operating characteristic curve for CHA 2 DS 2 -VASc score was 0.798 (95{\%} CI, 0.691−0.904). The CHA 2 DS 2 -VASc score could be used to stratify patients into two groups with different incidences of ischemic stroke (1.6{\%} vs. 14.4{\%}, p<0.001) at a cutoff value of 2. Conclusion: CHA 2 DS 2 -VASc score is useful in a prediction model for the risk of stroke after catheter ablation of typical AFL.",
author = "Jin, {Moo Nyun} and Changho Song and Kim, {Tae Hoon} and Uhm, {Jae Sun} and Pak, {Hui Nam} and Lee, {Moon Hyoung} and Boyoung Joung",
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CHA 2 DS 2 -VASC score in the prediction of ischemic stroke in patients after radiofrequency catheter ablation of typical atrial flutter . / Jin, Moo Nyun; Song, Changho; Kim, Tae Hoon; Uhm, Jae Sun; Pak, Hui Nam; Lee, Moon Hyoung; Joung, Boyoung.

In: Yonsei medical journal, Vol. 59, No. 2, 03.2018, p. 236-242.

Research output: Contribution to journalArticle

TY - JOUR

T1 - CHA 2 DS 2 -VASC score in the prediction of ischemic stroke in patients after radiofrequency catheter ablation of typical atrial flutter

AU - Jin, Moo Nyun

AU - Song, Changho

AU - Kim, Tae Hoon

AU - Uhm, Jae Sun

AU - Pak, Hui Nam

AU - Lee, Moon Hyoung

AU - Joung, Boyoung

PY - 2018/3

Y1 - 2018/3

N2 - Purpose: Despite undergoing successful catheter ablation of typical atrial flutter (AFL), patients remain at increased risk for ischemic stroke. However, data on risk prediction tools for the development of stroke after AFL ablation are lacking. This study investigates whether CHA 2 DS 2 -VASc score is useful for predicting ischemic stroke after successful ablation of typical AFL. Materials and Methods: A total of 293 patients (236 men, mean age 56.1±13.5 years) who underwent successful radiofrequency catheter ablation for typical AFL were included in this study. The clinical end point was occurrence of ischemic stroke during follow-up after AFL ablation. Results: During the follow-up period (60.8±45.9 months), ischemic stroke occurred in 18 (6%) patients at a median of 34 months (interquartile range, 13−65 months). CHA 2 DS 2 -VASc score [hazard ratio 2.104; 95% confidence interval (CI), 1.624−2.726; p<0.001] was an independent predictor for the occurrence of stroke after AFL ablation. The area under the receiver operating characteristic curve for CHA 2 DS 2 -VASc score was 0.798 (95% CI, 0.691−0.904). The CHA 2 DS 2 -VASc score could be used to stratify patients into two groups with different incidences of ischemic stroke (1.6% vs. 14.4%, p<0.001) at a cutoff value of 2. Conclusion: CHA 2 DS 2 -VASc score is useful in a prediction model for the risk of stroke after catheter ablation of typical AFL.

AB - Purpose: Despite undergoing successful catheter ablation of typical atrial flutter (AFL), patients remain at increased risk for ischemic stroke. However, data on risk prediction tools for the development of stroke after AFL ablation are lacking. This study investigates whether CHA 2 DS 2 -VASc score is useful for predicting ischemic stroke after successful ablation of typical AFL. Materials and Methods: A total of 293 patients (236 men, mean age 56.1±13.5 years) who underwent successful radiofrequency catheter ablation for typical AFL were included in this study. The clinical end point was occurrence of ischemic stroke during follow-up after AFL ablation. Results: During the follow-up period (60.8±45.9 months), ischemic stroke occurred in 18 (6%) patients at a median of 34 months (interquartile range, 13−65 months). CHA 2 DS 2 -VASc score [hazard ratio 2.104; 95% confidence interval (CI), 1.624−2.726; p<0.001] was an independent predictor for the occurrence of stroke after AFL ablation. The area under the receiver operating characteristic curve for CHA 2 DS 2 -VASc score was 0.798 (95% CI, 0.691−0.904). The CHA 2 DS 2 -VASc score could be used to stratify patients into two groups with different incidences of ischemic stroke (1.6% vs. 14.4%, p<0.001) at a cutoff value of 2. Conclusion: CHA 2 DS 2 -VASc score is useful in a prediction model for the risk of stroke after catheter ablation of typical AFL.

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