Challenges in the chemical synthesis of average sized proteins: sequential vs. convergent ligation of multiple peptide fragments.

Ji Yeon Lee, Duhee Bang

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

This review examines the challenges in the chemical synthesis of average sized proteins. Recent progress on sequential and convergent ligation methods, two approaches to the synthesis of proteins, is outlined. An examination of these challenges could aid in the process of finding new methodologies for the efficient chemical synthesis of average sized protein molecules. Copyright (c) 2010 Wiley Periodicals, Inc.

Original languageEnglish
Pages (from-to)441-447
Number of pages7
JournalBiopolymers
Volume94
Issue number4
DOIs
Publication statusPublished - 2010

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Peptide Fragments
Peptides
Ligation
Proteins
Molecules

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Biomaterials
  • Organic Chemistry

Cite this

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Challenges in the chemical synthesis of average sized proteins : sequential vs. convergent ligation of multiple peptide fragments. / Lee, Ji Yeon; Bang, Duhee.

In: Biopolymers, Vol. 94, No. 4, 2010, p. 441-447.

Research output: Contribution to journalReview article

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