Changes in biomechanically corrected intraocular pressure and dynamic corneal response parameters before and after transepithelial photorefractive keratectomy and femtosecond laser–assisted laser in situ keratomileusis

Hun Lee, Cynthia J. Roberts, Tae im Kim, Renato Ambrósio, Ahmed Elsheikh, David Sung Yong Kang

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Purpose To evaluate the changes in biomechanically corrected intraocular pressure (IOP) and new dynamic corneal response parameters measured by a dynamic Scheimpflug analyzer before and after transepithelial photorefractive keratectomy (PRK) and femtosecond laser–assisted laser in situ keratomileusis (LASIK). Setting Yonsei University College of Medicine and Eyereum Eye Clinic, Seoul, South Korea. Design Retrospective case series. Methods Medical records of patients having transepithelial PRK or femtosecond-assisted LASIK were examined. The primary outcome variables were biomechanically corrected IOP and dynamic corneal response parameters, including deformation amplitude ratio 2.0 mm, stiffness parameter at first applanation, Ambrósio relational thickness through the horizontal meridian, and integrated inverse radius before the procedure and 6 months postoperatively. Results Of the 129 patients (129 eyes) in the study, 65 had transepithelial PRK and 64 had femtosecond-assisted LASIK. No significant differences in biomechanically corrected IOP were noted before and after surgery. The deformation amplitude ratio 2.0 mm and integrated inverse radius increased, whereas the stiffness parameter at first applanation and the Ambrósio relational thickness through the horizontal meridian decreased after surgery (P <.001). The changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Using analysis of covariance, with refractive error change or corneal thickness change as a covariate, the changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Conclusions The dynamic Scheimpflug analyzer showed stable biomechanically corrected IOP measurement before and after surgery. The changes in dynamic corneal response parameters were smaller with transepithelial PRK than with femtosecond-assisted LASIK, indicating less of a biomechanical effect with transepithelial PRK.

Original languageEnglish
Pages (from-to)1495-1503
Number of pages9
JournalJournal of Cataract and Refractive Surgery
Volume43
Issue number12
DOIs
Publication statusPublished - 2017 Dec

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Photorefractive Keratectomy
Laser In Situ Keratomileusis
Intraocular Pressure
Meridians
Republic of Korea
Refractive Errors
Medical Records
Medicine

All Science Journal Classification (ASJC) codes

  • Surgery
  • Ophthalmology
  • Sensory Systems

Cite this

@article{d79cede4a88d4968971acbcfe894e301,
title = "Changes in biomechanically corrected intraocular pressure and dynamic corneal response parameters before and after transepithelial photorefractive keratectomy and femtosecond laser–assisted laser in situ keratomileusis",
abstract = "Purpose To evaluate the changes in biomechanically corrected intraocular pressure (IOP) and new dynamic corneal response parameters measured by a dynamic Scheimpflug analyzer before and after transepithelial photorefractive keratectomy (PRK) and femtosecond laser–assisted laser in situ keratomileusis (LASIK). Setting Yonsei University College of Medicine and Eyereum Eye Clinic, Seoul, South Korea. Design Retrospective case series. Methods Medical records of patients having transepithelial PRK or femtosecond-assisted LASIK were examined. The primary outcome variables were biomechanically corrected IOP and dynamic corneal response parameters, including deformation amplitude ratio 2.0 mm, stiffness parameter at first applanation, Ambr{\'o}sio relational thickness through the horizontal meridian, and integrated inverse radius before the procedure and 6 months postoperatively. Results Of the 129 patients (129 eyes) in the study, 65 had transepithelial PRK and 64 had femtosecond-assisted LASIK. No significant differences in biomechanically corrected IOP were noted before and after surgery. The deformation amplitude ratio 2.0 mm and integrated inverse radius increased, whereas the stiffness parameter at first applanation and the Ambr{\'o}sio relational thickness through the horizontal meridian decreased after surgery (P <.001). The changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Using analysis of covariance, with refractive error change or corneal thickness change as a covariate, the changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Conclusions The dynamic Scheimpflug analyzer showed stable biomechanically corrected IOP measurement before and after surgery. The changes in dynamic corneal response parameters were smaller with transepithelial PRK than with femtosecond-assisted LASIK, indicating less of a biomechanical effect with transepithelial PRK.",
author = "Hun Lee and Roberts, {Cynthia J.} and Kim, {Tae im} and Renato Ambr{\'o}sio and Ahmed Elsheikh and {Yong Kang}, {David Sung}",
year = "2017",
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language = "English",
volume = "43",
pages = "1495--1503",
journal = "Journal of Cataract and Refractive Surgery",
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Changes in biomechanically corrected intraocular pressure and dynamic corneal response parameters before and after transepithelial photorefractive keratectomy and femtosecond laser–assisted laser in situ keratomileusis. / Lee, Hun; Roberts, Cynthia J.; Kim, Tae im; Ambrósio, Renato; Elsheikh, Ahmed; Yong Kang, David Sung.

In: Journal of Cataract and Refractive Surgery, Vol. 43, No. 12, 12.2017, p. 1495-1503.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Changes in biomechanically corrected intraocular pressure and dynamic corneal response parameters before and after transepithelial photorefractive keratectomy and femtosecond laser–assisted laser in situ keratomileusis

AU - Lee, Hun

AU - Roberts, Cynthia J.

AU - Kim, Tae im

AU - Ambrósio, Renato

AU - Elsheikh, Ahmed

AU - Yong Kang, David Sung

PY - 2017/12

Y1 - 2017/12

N2 - Purpose To evaluate the changes in biomechanically corrected intraocular pressure (IOP) and new dynamic corneal response parameters measured by a dynamic Scheimpflug analyzer before and after transepithelial photorefractive keratectomy (PRK) and femtosecond laser–assisted laser in situ keratomileusis (LASIK). Setting Yonsei University College of Medicine and Eyereum Eye Clinic, Seoul, South Korea. Design Retrospective case series. Methods Medical records of patients having transepithelial PRK or femtosecond-assisted LASIK were examined. The primary outcome variables were biomechanically corrected IOP and dynamic corneal response parameters, including deformation amplitude ratio 2.0 mm, stiffness parameter at first applanation, Ambrósio relational thickness through the horizontal meridian, and integrated inverse radius before the procedure and 6 months postoperatively. Results Of the 129 patients (129 eyes) in the study, 65 had transepithelial PRK and 64 had femtosecond-assisted LASIK. No significant differences in biomechanically corrected IOP were noted before and after surgery. The deformation amplitude ratio 2.0 mm and integrated inverse radius increased, whereas the stiffness parameter at first applanation and the Ambrósio relational thickness through the horizontal meridian decreased after surgery (P <.001). The changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Using analysis of covariance, with refractive error change or corneal thickness change as a covariate, the changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Conclusions The dynamic Scheimpflug analyzer showed stable biomechanically corrected IOP measurement before and after surgery. The changes in dynamic corneal response parameters were smaller with transepithelial PRK than with femtosecond-assisted LASIK, indicating less of a biomechanical effect with transepithelial PRK.

AB - Purpose To evaluate the changes in biomechanically corrected intraocular pressure (IOP) and new dynamic corneal response parameters measured by a dynamic Scheimpflug analyzer before and after transepithelial photorefractive keratectomy (PRK) and femtosecond laser–assisted laser in situ keratomileusis (LASIK). Setting Yonsei University College of Medicine and Eyereum Eye Clinic, Seoul, South Korea. Design Retrospective case series. Methods Medical records of patients having transepithelial PRK or femtosecond-assisted LASIK were examined. The primary outcome variables were biomechanically corrected IOP and dynamic corneal response parameters, including deformation amplitude ratio 2.0 mm, stiffness parameter at first applanation, Ambrósio relational thickness through the horizontal meridian, and integrated inverse radius before the procedure and 6 months postoperatively. Results Of the 129 patients (129 eyes) in the study, 65 had transepithelial PRK and 64 had femtosecond-assisted LASIK. No significant differences in biomechanically corrected IOP were noted before and after surgery. The deformation amplitude ratio 2.0 mm and integrated inverse radius increased, whereas the stiffness parameter at first applanation and the Ambrósio relational thickness through the horizontal meridian decreased after surgery (P <.001). The changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Using analysis of covariance, with refractive error change or corneal thickness change as a covariate, the changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Conclusions The dynamic Scheimpflug analyzer showed stable biomechanically corrected IOP measurement before and after surgery. The changes in dynamic corneal response parameters were smaller with transepithelial PRK than with femtosecond-assisted LASIK, indicating less of a biomechanical effect with transepithelial PRK.

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