Purpose To evaluate the changes in biomechanically corrected intraocular pressure (IOP) and new dynamic corneal response parameters measured by a dynamic Scheimpflug analyzer before and after transepithelial photorefractive keratectomy (PRK) and femtosecond laser–assisted laser in situ keratomileusis (LASIK). Setting Yonsei University College of Medicine and Eyereum Eye Clinic, Seoul, South Korea. Design Retrospective case series. Methods Medical records of patients having transepithelial PRK or femtosecond-assisted LASIK were examined. The primary outcome variables were biomechanically corrected IOP and dynamic corneal response parameters, including deformation amplitude ratio 2.0 mm, stiffness parameter at first applanation, Ambrósio relational thickness through the horizontal meridian, and integrated inverse radius before the procedure and 6 months postoperatively. Results Of the 129 patients (129 eyes) in the study, 65 had transepithelial PRK and 64 had femtosecond-assisted LASIK. No significant differences in biomechanically corrected IOP were noted before and after surgery. The deformation amplitude ratio 2.0 mm and integrated inverse radius increased, whereas the stiffness parameter at first applanation and the Ambrósio relational thickness through the horizontal meridian decreased after surgery (P <.001). The changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Using analysis of covariance, with refractive error change or corneal thickness change as a covariate, the changes in deformation amplitude ratio 2.0 mm and integrated inverse radius were smaller in transepithelial PRK than femtosecond-assisted LASIK (P <.001). Conclusions The dynamic Scheimpflug analyzer showed stable biomechanically corrected IOP measurement before and after surgery. The changes in dynamic corneal response parameters were smaller with transepithelial PRK than with femtosecond-assisted LASIK, indicating less of a biomechanical effect with transepithelial PRK.
Bibliographical noteFunding Information:
Supported in part by Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (NRF-2016R1A2B4009626) and by the research fund of Catholic Kwandong University International St. Mary's Hospital (CKURF-201604900001), Incheon, South Korea. The funding agency had no role in the design or conduct of this study, collection, management, analysis, or interpretation of the data; preparation, review, or approval of the manuscript; or in the decision to submit the manuscript for publication.
Drs. Ambrósio and Roberts are consultants to and Dr. Elsheikh has received research funding from Oculus Optikgeräte GmbH. Dr. Kang is a consultant to Avedro, Inc. and Schwind eye-tech solutions GmbH & Co. KG. None of the other authors has a financial or proprietary interest in any material or method mentioned.
© 2017 ASCRS and ESCRS
All Science Journal Classification (ASJC) codes
- Sensory Systems