Changes in cardiovascular health status and risk of sudden cardiac death in older adults

Min Kim, Pil Sung Yang, Hee Tae Yu, Tae Hoon Kim, Eunsun Jang, Jae Sun Uhm, Hui Nam Pak, Moon Hyoung Lee, Boyoung Joung

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Cardiovascular health (CVH) status is associated with several cardiovascular outcomes; however, correlations between changes in CVH status and risk of sudden cardiac death (SCD) are unknown. We aimed to evaluate associations between changes in CVH status and risk of SCD and all-cause death in older adults. Materials and Methods: We used data from the Korea National Health Insurance Service-Senior cohort database (2005–2012). Six metrics from the American Heart Association (smoking, body mass index, physical activity, blood pressure, total cholesterol, and fasting blood glucose) were used to calculate CVH scores. Changes in CVH status between two health checkups were categorized as low to low, low to high, high to low, and high to high. Results: We included 105200 patients whose CVH status for an initial and follow-up health checkup (2-year interval) was available. During a median of 5.2 years of follow-up after a second health checkup, 688 SCDs occurred. Compared to patients with a persistent low CVH status, those with a consistently high CVH status had a reduced risk of SCD [adjusted hazard ratio (HR), 0.69; 95% confidence interval (CI), 0.56–0.86] and all-cause death (adjusted HR, 0.74; 95% CI, 0.69–0.78). The risk of all-cause death followed similar trends. However, an inconsistent linear relationship was observed for changes in CVH status and the risk of SCD, but not of all-cause death. Conclusion: Maintaining a high CVH status was associated with future risks of SCD and all-cause death among an older adult population.

Original languageEnglish
Pages (from-to)298-305
Number of pages8
JournalYonsei medical journal
Volume62
Issue number4
DOIs
Publication statusPublished - 2021

Bibliographical note

Funding Information:
National Health Information data were provided by the National Health Insurance Service (NHIS) of Korea. The authors would like to thank the NHIS for their cooperation. This study was supported by a research grant from the Korean Healthcare Technology R&D project funded by the Ministry of Health & Welfare (HI15C1200, HC19C0130) and a CMB-Yuhan research grant from Yonsei University College of Medicine (6-2019-0124).

Funding Information:
This study was supported by a research grant from the Korean Healthcare Technology R&D project funded by the Ministry of Health & Welfare (HI15C1200, HC19C0130) and a CMB-Yuhan research grant from Yonsei University College of Medicine (6-2019-0124).

Publisher Copyright:
© Yonsei University College of Medicine 2021.

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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