Changes in left ventricular function and dimension after surgical ventricular restoration with or without concomitant mitral valve procedure

Sak Lee, Byung Chul Chang, G. Nam Youn, Younglan Kwak, Kyung Jong Yoo

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: An association of mitral regurgitation (MR) with ischemic cardiomyopathy (I-CMP) increases the risk of heart failure and its surgical management remains controversial. Methods and Results: Between July 2001 and June 2006, a total of 49 patients with I-CMP underwent surgical ventricular restoration (SVR) and coronary revascularization with or without concomitant mitral annuloplasty (MAP). The mean age was 59.8 years, and all patients had New York Heart Association (NYHA) class III or IV heart failure (mean left ventricular ejection fraction (LVEF)=24.8%). Nineteen patients had MR>grade 3 (MR group). SVR and coronary artery bypass grafting were performed in all patients, and concomitant MAP was performed in the MR group. Echocardiography was performed preoperatively, postoperatively, and at mean of 19 months after operation. Preoperative left ventricular (LV) end-diastolic and end-systolic dimensions, left atrial volume index, and MR grade were statistically significantly increased in the MR group. On the early postoperative echocardiogram, mean LVEF was significantly improved, with reduction of LV dimensions, in both groups; however, at follow up, these parameters were more significantly improved in the MR group, but unchanged in non-MR group, reaching almost the same levels as the non-MR group. Conclusion: In patients with I-CMP, MR increases early and late mortality; however, after SVR and concomitant MAP, LV function seems to continuously improve with more significant reduction in the LV dimensions than in the non-MR group.

Original languageEnglish
Pages (from-to)1516-1520
Number of pages5
JournalCirculation Journal
Volume71
Issue number10
DOIs
Publication statusPublished - 2007 Oct 12

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Mitral Valve Insufficiency
Mitral Valve
Left Ventricular Function
Mitral Valve Annuloplasty
Cardiomyopathies
Stroke Volume
Heart Failure
Coronary Artery Bypass
Echocardiography
Mortality

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Physiology

Cite this

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title = "Changes in left ventricular function and dimension after surgical ventricular restoration with or without concomitant mitral valve procedure",
abstract = "Background: An association of mitral regurgitation (MR) with ischemic cardiomyopathy (I-CMP) increases the risk of heart failure and its surgical management remains controversial. Methods and Results: Between July 2001 and June 2006, a total of 49 patients with I-CMP underwent surgical ventricular restoration (SVR) and coronary revascularization with or without concomitant mitral annuloplasty (MAP). The mean age was 59.8 years, and all patients had New York Heart Association (NYHA) class III or IV heart failure (mean left ventricular ejection fraction (LVEF)=24.8{\%}). Nineteen patients had MR>grade 3 (MR group). SVR and coronary artery bypass grafting were performed in all patients, and concomitant MAP was performed in the MR group. Echocardiography was performed preoperatively, postoperatively, and at mean of 19 months after operation. Preoperative left ventricular (LV) end-diastolic and end-systolic dimensions, left atrial volume index, and MR grade were statistically significantly increased in the MR group. On the early postoperative echocardiogram, mean LVEF was significantly improved, with reduction of LV dimensions, in both groups; however, at follow up, these parameters were more significantly improved in the MR group, but unchanged in non-MR group, reaching almost the same levels as the non-MR group. Conclusion: In patients with I-CMP, MR increases early and late mortality; however, after SVR and concomitant MAP, LV function seems to continuously improve with more significant reduction in the LV dimensions than in the non-MR group.",
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Changes in left ventricular function and dimension after surgical ventricular restoration with or without concomitant mitral valve procedure. / Lee, Sak; Chang, Byung Chul; Youn, G. Nam; Kwak, Younglan; Yoo, Kyung Jong.

In: Circulation Journal, Vol. 71, No. 10, 12.10.2007, p. 1516-1520.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Changes in left ventricular function and dimension after surgical ventricular restoration with or without concomitant mitral valve procedure

AU - Lee, Sak

AU - Chang, Byung Chul

AU - Youn, G. Nam

AU - Kwak, Younglan

AU - Yoo, Kyung Jong

PY - 2007/10/12

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N2 - Background: An association of mitral regurgitation (MR) with ischemic cardiomyopathy (I-CMP) increases the risk of heart failure and its surgical management remains controversial. Methods and Results: Between July 2001 and June 2006, a total of 49 patients with I-CMP underwent surgical ventricular restoration (SVR) and coronary revascularization with or without concomitant mitral annuloplasty (MAP). The mean age was 59.8 years, and all patients had New York Heart Association (NYHA) class III or IV heart failure (mean left ventricular ejection fraction (LVEF)=24.8%). Nineteen patients had MR>grade 3 (MR group). SVR and coronary artery bypass grafting were performed in all patients, and concomitant MAP was performed in the MR group. Echocardiography was performed preoperatively, postoperatively, and at mean of 19 months after operation. Preoperative left ventricular (LV) end-diastolic and end-systolic dimensions, left atrial volume index, and MR grade were statistically significantly increased in the MR group. On the early postoperative echocardiogram, mean LVEF was significantly improved, with reduction of LV dimensions, in both groups; however, at follow up, these parameters were more significantly improved in the MR group, but unchanged in non-MR group, reaching almost the same levels as the non-MR group. Conclusion: In patients with I-CMP, MR increases early and late mortality; however, after SVR and concomitant MAP, LV function seems to continuously improve with more significant reduction in the LV dimensions than in the non-MR group.

AB - Background: An association of mitral regurgitation (MR) with ischemic cardiomyopathy (I-CMP) increases the risk of heart failure and its surgical management remains controversial. Methods and Results: Between July 2001 and June 2006, a total of 49 patients with I-CMP underwent surgical ventricular restoration (SVR) and coronary revascularization with or without concomitant mitral annuloplasty (MAP). The mean age was 59.8 years, and all patients had New York Heart Association (NYHA) class III or IV heart failure (mean left ventricular ejection fraction (LVEF)=24.8%). Nineteen patients had MR>grade 3 (MR group). SVR and coronary artery bypass grafting were performed in all patients, and concomitant MAP was performed in the MR group. Echocardiography was performed preoperatively, postoperatively, and at mean of 19 months after operation. Preoperative left ventricular (LV) end-diastolic and end-systolic dimensions, left atrial volume index, and MR grade were statistically significantly increased in the MR group. On the early postoperative echocardiogram, mean LVEF was significantly improved, with reduction of LV dimensions, in both groups; however, at follow up, these parameters were more significantly improved in the MR group, but unchanged in non-MR group, reaching almost the same levels as the non-MR group. Conclusion: In patients with I-CMP, MR increases early and late mortality; however, after SVR and concomitant MAP, LV function seems to continuously improve with more significant reduction in the LV dimensions than in the non-MR group.

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