Changing trends in histologic types of lung cancer during the last decade (1981-1990) in Korea: a hospital-based study

Jin Hyuk Choi, Hyun Cheol Chung, Nae Chun Yoo, Hye Ran Lee, Kyung Hee Lee, Won Choi, Ho Yeong Lim, Eun Hee Koh, Joo Hang Kim, Jae Kyung Roh, Sung Kyu Kim, Won Young Lee, Byung Soo Kim

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Abstract

A review of the histopathology and past history of 2229 patients with primary lung cancer diagnosed at the Yonsei University Medical Center from 1981 to 1990 was performed to investigate the changes in histologic types and the relationship to smoking history. The most frequent histologic type of lung cancer was squamous cell carcinoma (956 patients, 54.0%) followed by adenocarcinoma (311 patients, 17.6%) in males (1772 patients), and adenocarcinoma (206 patients, 45.1%) followed by squamous cell carcinoma (126 patients, 27.6%) in females (457 patients). In both sexes, the predominant type was adenocarcinoma under the age of 40, whereas squamous cell carcinoma was the most frequent type above the age of 40. While squamous cell carcinoma decreased over 10 years (54.3% in 1981, 44.3% in 1990), adenocarcinoma showed a gradually increased incidence (17.0% in 1981, 28.3% in 1990) in both sexes, and the proportion of small cell carcinoma and large cell carcinoma remained unchanged. These changes in histologic type were more prominent in non-smokers. In conclusion, the increasing incidence of adenocarcinoma in both sexes, especially in non-smokers, suggests the possible presence of etiologic factors other than smoking, such as environmental pollution.

Original languageEnglish
Pages (from-to)287-296
Number of pages10
JournalLung Cancer
Volume10
Issue number5-6
DOIs
Publication statusPublished - 1994 Mar

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Korea
Lung Neoplasms
Adenocarcinoma
Squamous Cell Carcinoma
Smoking
Large Cell Carcinoma
Environmental Pollution
Small Cell Carcinoma
Incidence
History

All Science Journal Classification (ASJC) codes

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

Cite this

Choi, Jin Hyuk ; Chung, Hyun Cheol ; Yoo, Nae Chun ; Lee, Hye Ran ; Lee, Kyung Hee ; Choi, Won ; Lim, Ho Yeong ; Koh, Eun Hee ; Kim, Joo Hang ; Roh, Jae Kyung ; Kim, Sung Kyu ; Lee, Won Young ; Kim, Byung Soo. / Changing trends in histologic types of lung cancer during the last decade (1981-1990) in Korea : a hospital-based study. In: Lung Cancer. 1994 ; Vol. 10, No. 5-6. pp. 287-296.
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abstract = "A review of the histopathology and past history of 2229 patients with primary lung cancer diagnosed at the Yonsei University Medical Center from 1981 to 1990 was performed to investigate the changes in histologic types and the relationship to smoking history. The most frequent histologic type of lung cancer was squamous cell carcinoma (956 patients, 54.0{\%}) followed by adenocarcinoma (311 patients, 17.6{\%}) in males (1772 patients), and adenocarcinoma (206 patients, 45.1{\%}) followed by squamous cell carcinoma (126 patients, 27.6{\%}) in females (457 patients). In both sexes, the predominant type was adenocarcinoma under the age of 40, whereas squamous cell carcinoma was the most frequent type above the age of 40. While squamous cell carcinoma decreased over 10 years (54.3{\%} in 1981, 44.3{\%} in 1990), adenocarcinoma showed a gradually increased incidence (17.0{\%} in 1981, 28.3{\%} in 1990) in both sexes, and the proportion of small cell carcinoma and large cell carcinoma remained unchanged. These changes in histologic type were more prominent in non-smokers. In conclusion, the increasing incidence of adenocarcinoma in both sexes, especially in non-smokers, suggests the possible presence of etiologic factors other than smoking, such as environmental pollution.",
author = "Choi, {Jin Hyuk} and Chung, {Hyun Cheol} and Yoo, {Nae Chun} and Lee, {Hye Ran} and Lee, {Kyung Hee} and Won Choi and Lim, {Ho Yeong} and Koh, {Eun Hee} and Kim, {Joo Hang} and Roh, {Jae Kyung} and Kim, {Sung Kyu} and Lee, {Won Young} and Kim, {Byung Soo}",
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Choi, JH, Chung, HC, Yoo, NC, Lee, HR, Lee, KH, Choi, W, Lim, HY, Koh, EH, Kim, JH, Roh, JK, Kim, SK, Lee, WY & Kim, BS 1994, 'Changing trends in histologic types of lung cancer during the last decade (1981-1990) in Korea: a hospital-based study', Lung Cancer, vol. 10, no. 5-6, pp. 287-296. https://doi.org/10.1016/0169-5002(94)90658-0

Changing trends in histologic types of lung cancer during the last decade (1981-1990) in Korea : a hospital-based study. / Choi, Jin Hyuk; Chung, Hyun Cheol; Yoo, Nae Chun; Lee, Hye Ran; Lee, Kyung Hee; Choi, Won; Lim, Ho Yeong; Koh, Eun Hee; Kim, Joo Hang; Roh, Jae Kyung; Kim, Sung Kyu; Lee, Won Young; Kim, Byung Soo.

In: Lung Cancer, Vol. 10, No. 5-6, 03.1994, p. 287-296.

Research output: Contribution to journalArticle

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T1 - Changing trends in histologic types of lung cancer during the last decade (1981-1990) in Korea

T2 - a hospital-based study

AU - Choi, Jin Hyuk

AU - Chung, Hyun Cheol

AU - Yoo, Nae Chun

AU - Lee, Hye Ran

AU - Lee, Kyung Hee

AU - Choi, Won

AU - Lim, Ho Yeong

AU - Koh, Eun Hee

AU - Kim, Joo Hang

AU - Roh, Jae Kyung

AU - Kim, Sung Kyu

AU - Lee, Won Young

AU - Kim, Byung Soo

PY - 1994/3

Y1 - 1994/3

N2 - A review of the histopathology and past history of 2229 patients with primary lung cancer diagnosed at the Yonsei University Medical Center from 1981 to 1990 was performed to investigate the changes in histologic types and the relationship to smoking history. The most frequent histologic type of lung cancer was squamous cell carcinoma (956 patients, 54.0%) followed by adenocarcinoma (311 patients, 17.6%) in males (1772 patients), and adenocarcinoma (206 patients, 45.1%) followed by squamous cell carcinoma (126 patients, 27.6%) in females (457 patients). In both sexes, the predominant type was adenocarcinoma under the age of 40, whereas squamous cell carcinoma was the most frequent type above the age of 40. While squamous cell carcinoma decreased over 10 years (54.3% in 1981, 44.3% in 1990), adenocarcinoma showed a gradually increased incidence (17.0% in 1981, 28.3% in 1990) in both sexes, and the proportion of small cell carcinoma and large cell carcinoma remained unchanged. These changes in histologic type were more prominent in non-smokers. In conclusion, the increasing incidence of adenocarcinoma in both sexes, especially in non-smokers, suggests the possible presence of etiologic factors other than smoking, such as environmental pollution.

AB - A review of the histopathology and past history of 2229 patients with primary lung cancer diagnosed at the Yonsei University Medical Center from 1981 to 1990 was performed to investigate the changes in histologic types and the relationship to smoking history. The most frequent histologic type of lung cancer was squamous cell carcinoma (956 patients, 54.0%) followed by adenocarcinoma (311 patients, 17.6%) in males (1772 patients), and adenocarcinoma (206 patients, 45.1%) followed by squamous cell carcinoma (126 patients, 27.6%) in females (457 patients). In both sexes, the predominant type was adenocarcinoma under the age of 40, whereas squamous cell carcinoma was the most frequent type above the age of 40. While squamous cell carcinoma decreased over 10 years (54.3% in 1981, 44.3% in 1990), adenocarcinoma showed a gradually increased incidence (17.0% in 1981, 28.3% in 1990) in both sexes, and the proportion of small cell carcinoma and large cell carcinoma remained unchanged. These changes in histologic type were more prominent in non-smokers. In conclusion, the increasing incidence of adenocarcinoma in both sexes, especially in non-smokers, suggests the possible presence of etiologic factors other than smoking, such as environmental pollution.

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