Characteristics of hypertension subtypes and treatment outcome among elderly Korean hypertensives

Suk Won Choi, Min Kyu Kim, Seong Woo Han, Sung Hea Kim, Hyun Joong Kim, Seok Min Kang, Dae Kyeong Kim, Byung Soo Kim, Won Ho Kim, Jang Young Kim, Hee Yeol Kim, Jay Young Rhew, Keum Soo Park, Kyoung Im Cho, Myung Ho Jeong, Yong Suk Jeong, Kyu Hyung Ryu

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

There are limited data about characteristics of hypertension subtypes in Asian hypertensive patients and their impacts on treatment of hypertension. This prospective, multi-center, observational study evaluated 2439 hypertensive patients. (<60 years) Inadequately controlled and drug-naïve patients were categorized into three hypertension subtypes (isolated systolic hypertension [ISH], combined systolic/diastolic hypertension [SDH], and isolated diastolic hypertension [IDH]), and proportions of each hypertension subtype were evaluated. After 6-month strict treatments, we compared the characteristics of patients who did not achieve target BP with those who did. In overall population, ISH was the most common subtype (53.2%; 1297/2439). However, in drug-naïve patients, SDH was the predominant hypertension subtype (59.6%; 260/436). Notably, the proportion of ISH was substantially lower than previously known data. Predictors associated with failure of reaching target BP were old age (>70 years), hypertension awareness, and baseline systolic blood pressure (<160 mm Hg) for total patients. In drug naïve patients, hypertension awareness, ISH, and microalbuminuria were associated with treatment failure. These findings might have an impact on the evaluations and antihypertensive treatments of elderly Korean patients.

Original languageEnglish
Pages (from-to)246-253
Number of pages8
JournalJournal of the American Society of Hypertension
Volume8
Issue number4
DOIs
Publication statusPublished - 2014 Apr

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Hypertension
Blood Pressure
Treatment Failure
Antihypertensive Agents
Observational Studies
Therapeutics
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Choi, Suk Won ; Kim, Min Kyu ; Han, Seong Woo ; Kim, Sung Hea ; Kim, Hyun Joong ; Kang, Seok Min ; Kim, Dae Kyeong ; Kim, Byung Soo ; Kim, Won Ho ; Kim, Jang Young ; Kim, Hee Yeol ; Rhew, Jay Young ; Park, Keum Soo ; Cho, Kyoung Im ; Jeong, Myung Ho ; Jeong, Yong Suk ; Ryu, Kyu Hyung. / Characteristics of hypertension subtypes and treatment outcome among elderly Korean hypertensives. In: Journal of the American Society of Hypertension. 2014 ; Vol. 8, No. 4. pp. 246-253.
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title = "Characteristics of hypertension subtypes and treatment outcome among elderly Korean hypertensives",
abstract = "There are limited data about characteristics of hypertension subtypes in Asian hypertensive patients and their impacts on treatment of hypertension. This prospective, multi-center, observational study evaluated 2439 hypertensive patients. (<60 years) Inadequately controlled and drug-na{\"i}ve patients were categorized into three hypertension subtypes (isolated systolic hypertension [ISH], combined systolic/diastolic hypertension [SDH], and isolated diastolic hypertension [IDH]), and proportions of each hypertension subtype were evaluated. After 6-month strict treatments, we compared the characteristics of patients who did not achieve target BP with those who did. In overall population, ISH was the most common subtype (53.2{\%}; 1297/2439). However, in drug-na{\"i}ve patients, SDH was the predominant hypertension subtype (59.6{\%}; 260/436). Notably, the proportion of ISH was substantially lower than previously known data. Predictors associated with failure of reaching target BP were old age (>70 years), hypertension awareness, and baseline systolic blood pressure (<160 mm Hg) for total patients. In drug na{\"i}ve patients, hypertension awareness, ISH, and microalbuminuria were associated with treatment failure. These findings might have an impact on the evaluations and antihypertensive treatments of elderly Korean patients.",
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Choi, SW, Kim, MK, Han, SW, Kim, SH, Kim, HJ, Kang, SM, Kim, DK, Kim, BS, Kim, WH, Kim, JY, Kim, HY, Rhew, JY, Park, KS, Cho, KI, Jeong, MH, Jeong, YS & Ryu, KH 2014, 'Characteristics of hypertension subtypes and treatment outcome among elderly Korean hypertensives', Journal of the American Society of Hypertension, vol. 8, no. 4, pp. 246-253. https://doi.org/10.1016/j.jash.2014.01.004

Characteristics of hypertension subtypes and treatment outcome among elderly Korean hypertensives. / Choi, Suk Won; Kim, Min Kyu; Han, Seong Woo; Kim, Sung Hea; Kim, Hyun Joong; Kang, Seok Min; Kim, Dae Kyeong; Kim, Byung Soo; Kim, Won Ho; Kim, Jang Young; Kim, Hee Yeol; Rhew, Jay Young; Park, Keum Soo; Cho, Kyoung Im; Jeong, Myung Ho; Jeong, Yong Suk; Ryu, Kyu Hyung.

In: Journal of the American Society of Hypertension, Vol. 8, No. 4, 04.2014, p. 246-253.

Research output: Contribution to journalArticle

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T1 - Characteristics of hypertension subtypes and treatment outcome among elderly Korean hypertensives

AU - Choi, Suk Won

AU - Kim, Min Kyu

AU - Han, Seong Woo

AU - Kim, Sung Hea

AU - Kim, Hyun Joong

AU - Kang, Seok Min

AU - Kim, Dae Kyeong

AU - Kim, Byung Soo

AU - Kim, Won Ho

AU - Kim, Jang Young

AU - Kim, Hee Yeol

AU - Rhew, Jay Young

AU - Park, Keum Soo

AU - Cho, Kyoung Im

AU - Jeong, Myung Ho

AU - Jeong, Yong Suk

AU - Ryu, Kyu Hyung

PY - 2014/4

Y1 - 2014/4

N2 - There are limited data about characteristics of hypertension subtypes in Asian hypertensive patients and their impacts on treatment of hypertension. This prospective, multi-center, observational study evaluated 2439 hypertensive patients. (<60 years) Inadequately controlled and drug-naïve patients were categorized into three hypertension subtypes (isolated systolic hypertension [ISH], combined systolic/diastolic hypertension [SDH], and isolated diastolic hypertension [IDH]), and proportions of each hypertension subtype were evaluated. After 6-month strict treatments, we compared the characteristics of patients who did not achieve target BP with those who did. In overall population, ISH was the most common subtype (53.2%; 1297/2439). However, in drug-naïve patients, SDH was the predominant hypertension subtype (59.6%; 260/436). Notably, the proportion of ISH was substantially lower than previously known data. Predictors associated with failure of reaching target BP were old age (>70 years), hypertension awareness, and baseline systolic blood pressure (<160 mm Hg) for total patients. In drug naïve patients, hypertension awareness, ISH, and microalbuminuria were associated with treatment failure. These findings might have an impact on the evaluations and antihypertensive treatments of elderly Korean patients.

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