Abstract
During DNA sequence analysis of cosmid L373 from the Mycobacterium leprae genome, an open reading frame of 1.4 kb encoding a protein with some homology to the immunodominant 34-kDa protein of Mycobacterium paratuberculosis, but lacking significant serological activity, was detected. The DNA sequence predicted a signal peptide with a modified lipoprotein consensus sequence, but the protein proved to be devoid of lipid attachment.
| Original language | English |
|---|---|
| Pages (from-to) | 5576-5579 |
| Number of pages | 4 |
| Journal | Infection and Immunity |
| Volume | 66 |
| Issue number | 11 |
| Publication status | Published - 1998 Dec 1 |
All Science Journal Classification (ASJC) codes
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases
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Silbaq, F. S., Cho, S. N., Cole, S. T., & Brennan, P. J. (1998). Characterization of a 34-kilodalton protein of Mycobacterium leprae that is isologous to the immunodominant 34-kilodalton antigen of Mycobacterium paratuberculosis. Infection and Immunity, 66(11), 5576-5579.