Abstract
During DNA sequence analysis of cosmid L373 from the Mycobacterium leprae genome, an open reading frame of 1.4 kb encoding a protein with some homology to the immunodominant 34-kDa protein of Mycobacterium paratuberculosis, but lacking significant serological activity, was detected. The DNA sequence predicted a signal peptide with a modified lipoprotein consensus sequence, but the protein proved to be devoid of lipid attachment.
| Original language | English |
|---|---|
| Pages (from-to) | 5576-5579 |
| Number of pages | 4 |
| Journal | Infection and Immunity |
| Volume | 66 |
| Issue number | 11 |
| Publication status | Published - 1998 Dec 1 |
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All Science Journal Classification (ASJC) codes
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases
Cite this
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Characterization of a 34-kilodalton protein of Mycobacterium leprae that is isologous to the immunodominant 34-kilodalton antigen of Mycobacterium paratuberculosis. / Silbaq, Fauzi S.; Cho, Sangnae; Cole, Stewart T.; Brennan, Patrick J.
In: Infection and Immunity, Vol. 66, No. 11, 01.12.1998, p. 5576-5579.Research output: Contribution to journal › Article
TY - JOUR
T1 - Characterization of a 34-kilodalton protein of Mycobacterium leprae that is isologous to the immunodominant 34-kilodalton antigen of Mycobacterium paratuberculosis
AU - Silbaq, Fauzi S.
AU - Cho, Sangnae
AU - Cole, Stewart T.
AU - Brennan, Patrick J.
PY - 1998/12/1
Y1 - 1998/12/1
N2 - During DNA sequence analysis of cosmid L373 from the Mycobacterium leprae genome, an open reading frame of 1.4 kb encoding a protein with some homology to the immunodominant 34-kDa protein of Mycobacterium paratuberculosis, but lacking significant serological activity, was detected. The DNA sequence predicted a signal peptide with a modified lipoprotein consensus sequence, but the protein proved to be devoid of lipid attachment.
AB - During DNA sequence analysis of cosmid L373 from the Mycobacterium leprae genome, an open reading frame of 1.4 kb encoding a protein with some homology to the immunodominant 34-kDa protein of Mycobacterium paratuberculosis, but lacking significant serological activity, was detected. The DNA sequence predicted a signal peptide with a modified lipoprotein consensus sequence, but the protein proved to be devoid of lipid attachment.
UR - http://www.scopus.com/inward/record.url?scp=0032410807&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032410807&partnerID=8YFLogxK
M3 - Article
VL - 66
SP - 5576
EP - 5579
JO - Infection and Immunity
JF - Infection and Immunity
SN - 0019-9567
IS - 11
ER -