Abstract
We show that terahertz (THz) time-domain spectroscopy (TDS) can be used to characterize the blood. The complex optical constants of blood and its constituents, such as water, plasma, and red blood cells (RBCs), were obtained in the THz frequency region. The volume percentage of RBCs in blood was extracted and compared with the conventional RBC counter results. The THz absorption constants are shown to vary linearly with the RBC concentration in both normal saline and whole blood. The excellent linearity between the THz signal and the RBC concentration was also confirmed in a polyurethane resin tube using a THz imaging method. These results demonstrate that THz-TDS imaging can facilitate the quantitative analysis of blood.
| Original language | English |
|---|---|
| Article number | 107008 |
| Journal | Journal of Biomedical Optics |
| Volume | 18 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2013 Oct 1 |
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All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Biomedical Engineering
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Characterization of blood using terahertz waves. / Jeong, Kiyoung; Huh, yongmin; Kim, Sang Hoon; Park, Yeonji; Son, Joo Hiuk; Oh, Seung Jae; Suh, Jinsuck.
In: Journal of Biomedical Optics, Vol. 18, No. 10, 107008, 01.10.2013.Research output: Contribution to journal › Article
TY - JOUR
T1 - Characterization of blood using terahertz waves
AU - Jeong, Kiyoung
AU - Huh, yongmin
AU - Kim, Sang Hoon
AU - Park, Yeonji
AU - Son, Joo Hiuk
AU - Oh, Seung Jae
AU - Suh, Jinsuck
PY - 2013/10/1
Y1 - 2013/10/1
N2 - We show that terahertz (THz) time-domain spectroscopy (TDS) can be used to characterize the blood. The complex optical constants of blood and its constituents, such as water, plasma, and red blood cells (RBCs), were obtained in the THz frequency region. The volume percentage of RBCs in blood was extracted and compared with the conventional RBC counter results. The THz absorption constants are shown to vary linearly with the RBC concentration in both normal saline and whole blood. The excellent linearity between the THz signal and the RBC concentration was also confirmed in a polyurethane resin tube using a THz imaging method. These results demonstrate that THz-TDS imaging can facilitate the quantitative analysis of blood.
AB - We show that terahertz (THz) time-domain spectroscopy (TDS) can be used to characterize the blood. The complex optical constants of blood and its constituents, such as water, plasma, and red blood cells (RBCs), were obtained in the THz frequency region. The volume percentage of RBCs in blood was extracted and compared with the conventional RBC counter results. The THz absorption constants are shown to vary linearly with the RBC concentration in both normal saline and whole blood. The excellent linearity between the THz signal and the RBC concentration was also confirmed in a polyurethane resin tube using a THz imaging method. These results demonstrate that THz-TDS imaging can facilitate the quantitative analysis of blood.
UR - http://www.scopus.com/inward/record.url?scp=84892649592&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84892649592&partnerID=8YFLogxK
U2 - 10.1117/1.JBO.18.10.107008
DO - 10.1117/1.JBO.18.10.107008
M3 - Article
VL - 18
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
SN - 1083-3668
IS - 10
M1 - 107008
ER -