Characterization of clinicopathological features of tubal cavernous hemangioma

Gun Yoon, Hyun Soo Kim

Research output: Contribution to journalArticlepeer-review


Hemangioma is a benign tumor of vascular origin. Although hemangiomas are observed quite frequently, particularly in the skin and soft tissue, the rarity with which they are encountered in the fallopian tube makes the present study worth reporting in the literature. Cavernous hemangiomas of the fallopian tube are rare benign tumors that have been documented to date as isolated case reports only. Here we demonstrate a rare case of incidentally detected tubal cavernous hemangioma in a 49-year-old woman who underwent hysterectomy with right salpingo-oophorectomy for high-grade squamous intraepithelial lesion of the uterine cervix and an endometriotic cyst of the right ovary. Histopathological examination of a thickened tubal segment revealed a 1.2-cm relatively well-circumscribed nodular lesion consisting of dilated cavernous spaces filled with red blood cells. The majority of the vessels were thin-walled. The lining endothelium had bland-looking nuclei without cytologic atypia or mitotic figures. The tubal epithelium showed no pathological abnormalities. Strong and uniform CD31 and CD34 immunoreactivity in the lining endothelial cells confirmed the diagnosis of a benign vascular tumor. We also conducted a thorough review of the relevant literature with respect to the epidemiology, clinical manifestation, pathology, immunophenotype, and treatment options for hemangiomas arising in the fallopian tube.

Original languageEnglish
Pages (from-to)7476-7481
Number of pages6
JournalInternational Journal of Clinical and Experimental Pathology
Issue number7
Publication statusPublished - 2016

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology


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