Characterization of neuron signaling using microelectrode array combined with fast and precise cooling device for cryoanesthesia

Jaehyun Kim, Jong Seung Lee, Soyeon Noh, Nuree Lee, Jungchul Lee, Taesung Kim, Gunho Kim, Seung Woo Cho, Jungyul Park

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cryoanesthesia technology is effective on treatment of a skin surface as a purely physical technique without side effects, and study of cryoanesthesia in cellular level are need to improve its technology but there has been a lack of its study so far. Here, we introduce a novel platform for cryo-neuromodulation, which is composed of a microelectrode array (MEA) system and a high-speed and precise probe type cooling device that provides localized cooling temperature. We investigate the potential of cryo-neuromodulation by exploring temperature conditions (temperature and duration time) that cause block and recovery of neuron signal without cell damages.

Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages787-788
Number of pages2
ISBN (Electronic)9781733419000
Publication statusPublished - 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: 2019 Oct 272019 Oct 31

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Country/TerritorySwitzerland
CityBasel
Period19/10/2719/10/31

Bibliographical note

Funding Information:
This work was supported by project for National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (2017R1A4A1015564) and the Korea Environment Industry & Technology Institute (KEITI) through its Ecological Imitation-based Environmental Pollution Management Technology Development Project, and funded by the Korea Ministry of Environment (MOE) (2019002790007).

Publisher Copyright:
© 2019 CBMS-0001.

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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