Characterization of protein-immobilized polystyrene nanoparticles using impedance spectroscopy

Soo In Park, Sang Yup Lee

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A novel approach for characterization of non-conductive protein-immobilized nanoparticles using AC impedance spectroscopy combined with conductive atomic force microscopy was examined. As AC impedance spectroscopy can provide information on diverse electrical properties such as capacitance and inductance, it is applicable to the characterization of non-conductive substances. Several non-conductive protein-immobilized polystyrene nanoparticles were analyzed using AC impedance spectroscopy, and their impedance spectra were used as markers for nanoparticle identification. Analyses of impedance signals using an electrical circuit model established that the capacitance and inductance of each nanoparticle changed with the adsorbed protein and that impedance spectral differences were characteristic properties of the proteins. From this study, AC impedance spectroscopy was shown to be a useful tool for characterization of non-conductive nanoparticles and is expected to be applicable to the development of sensors for nanomaterials.

Original languageEnglish
Pages (from-to)7965-7969
Number of pages5
JournalJournal of Nanoscience and Nanotechnology
Volume14
Issue number10
DOIs
Publication statusPublished - 2014 Jan 1

Fingerprint

Immobilized Proteins
Dielectric Spectroscopy
Polystyrenes
Nanoparticles
polystyrene
Spectroscopy
impedance
proteins
Proteins
nanoparticles
Electric Impedance
alternating current
spectroscopy
Inductance
Capacitance
inductance
Nanostructures
Atomic Force Microscopy
capacitance
Nanostructured materials

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)
  • Condensed Matter Physics

Cite this

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abstract = "A novel approach for characterization of non-conductive protein-immobilized nanoparticles using AC impedance spectroscopy combined with conductive atomic force microscopy was examined. As AC impedance spectroscopy can provide information on diverse electrical properties such as capacitance and inductance, it is applicable to the characterization of non-conductive substances. Several non-conductive protein-immobilized polystyrene nanoparticles were analyzed using AC impedance spectroscopy, and their impedance spectra were used as markers for nanoparticle identification. Analyses of impedance signals using an electrical circuit model established that the capacitance and inductance of each nanoparticle changed with the adsorbed protein and that impedance spectral differences were characteristic properties of the proteins. From this study, AC impedance spectroscopy was shown to be a useful tool for characterization of non-conductive nanoparticles and is expected to be applicable to the development of sensors for nanomaterials.",
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Characterization of protein-immobilized polystyrene nanoparticles using impedance spectroscopy. / Park, Soo In; Lee, Sang Yup.

In: Journal of Nanoscience and Nanotechnology, Vol. 14, No. 10, 01.01.2014, p. 7965-7969.

Research output: Contribution to journalArticle

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