Characterization of solid UV cross-linked PEGDA for biological applications

David Castro, Patrick Ingram, Rimantas Kodzius, David Conchouso, Euisik Yoon, Ian G. Foulds

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Citations (Scopus)

Abstract

This paper reports on solid UV cross-linked Poly(ethylene)-glycol- diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.

Original languageEnglish
Title of host publicationIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages457-460
Number of pages4
DOIs
Publication statusPublished - 2013 Apr 2
EventIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
Duration: 2013 Jan 202013 Jan 24

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
CountryTaiwan, Province of China
CityTaipei
Period13/1/2013/1/24

Fingerprint

polymerase chain reaction
Polyethylene glycols
glycols
Polymerase chain reaction
ethylene
viability
attachment
Cells
microfluidic devices
biocompatibility
curing
Biocompatibility
Cell culture
Microfluidics
Curing
chips
poly(ethylene glycol)diacrylate

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Castro, D., Ingram, P., Kodzius, R., Conchouso, D., Yoon, E., & Foulds, I. G. (2013). Characterization of solid UV cross-linked PEGDA for biological applications. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 (pp. 457-460). [6474277] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2013.6474277
Castro, David ; Ingram, Patrick ; Kodzius, Rimantas ; Conchouso, David ; Yoon, Euisik ; Foulds, Ian G. / Characterization of solid UV cross-linked PEGDA for biological applications. IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. pp. 457-460 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).
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abstract = "This paper reports on solid UV cross-linked Poly(ethylene)-glycol- diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.",
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Castro, D, Ingram, P, Kodzius, R, Conchouso, D, Yoon, E & Foulds, IG 2013, Characterization of solid UV cross-linked PEGDA for biological applications. in IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013., 6474277, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 457-460, IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013, Taipei, Taiwan, Province of China, 13/1/20. https://doi.org/10.1109/MEMSYS.2013.6474277

Characterization of solid UV cross-linked PEGDA for biological applications. / Castro, David; Ingram, Patrick; Kodzius, Rimantas; Conchouso, David; Yoon, Euisik; Foulds, Ian G.

IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 457-460 6474277 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Castro D, Ingram P, Kodzius R, Conchouso D, Yoon E, Foulds IG. Characterization of solid UV cross-linked PEGDA for biological applications. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 457-460. 6474277. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2013.6474277