Chelation-Assisted C-H and C-C Bond Activation of Allylic Alcohols by a Rh(I) Catalyst under Microwave Irradiation

Chang Hee Lee, Chul Ho Jun

Research output: Contribution to journalArticle

Abstract

Chelation-assisted Rh(I)-catalyzed ketone synthesis from allylic alcohols and alkenes through C-H and C-C bond activations under microwave irradiation was developed. Aldimine is formed via olefin isomerization of allyl alcohol under Rh(I) catalysis and condensation with 2-amino-3-picoline, followed by continuous C-H and C-C bond activations to produce a dialkyl ketone. The addition of piperidine accelerates the reaction rate by promoting aldimine formation under microwave conditions.

Original languageEnglish
Pages (from-to)736-741
Number of pages6
JournalSynlett
Volume29
Issue number6
DOIs
Publication statusPublished - 2018 Apr 3

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All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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