Chelation-Assisted C-H and C-C Bond Activation of Allylic Alcohols by a Rh(I) Catalyst under Microwave Irradiation

Chang Hee Lee, Chul Ho Jun

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Chelation-assisted Rh(I)-catalyzed ketone synthesis from allylic alcohols and alkenes through C-H and C-C bond activations under microwave irradiation was developed. Aldimine is formed via olefin isomerization of allyl alcohol under Rh(I) catalysis and condensation with 2-amino-3-picoline, followed by continuous C-H and C-C bond activations to produce a dialkyl ketone. The addition of piperidine accelerates the reaction rate by promoting aldimine formation under microwave conditions.

Original languageEnglish
Pages (from-to)736-741
Number of pages6
JournalSynlett
Volume29
Issue number6
DOIs
Publication statusPublished - 2018 Apr 3

Bibliographical note

Funding Information:
This study was financially supported by a grant from the National Research Foundation of Korea (NRF) (Grant 2016-R-1A2b4009460).Noaitnal Research Foundoaitn Koera 2(016-R-1A2b400946)

Publisher Copyright:
© Georg Thieme Verlag Stuttgart New York.

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Fingerprint Dive into the research topics of 'Chelation-Assisted C-H and C-C Bond Activation of Allylic Alcohols by a Rh(I) Catalyst under Microwave Irradiation'. Together they form a unique fingerprint.

Cite this