Herein we describe the chelation-assisted C-H and C-C bond activation of carbonyl compounds by RhI catalysts. Hydroacylation of olefins was accomplished by utilizing 2-amino-3-picoline as a chelation auxiliary. The same strategy was employed for the C-C bond activation of unstrained ketones. Allylamine 24 was devised as a synthon of formaldehyde. Hydroiminoacylation of alkynes with allylamine 24 was applied to the alkyne cleavage by the aid of cyclohexylamine.
|Number of pages||7|
|Journal||Chemistry - A European Journal|
|Publication status||Published - 2002 Jun 3|
All Science Journal Classification (ASJC) codes
- Organic Chemistry