The C-H bond of aldehyde can be cleaved by a transition metal complex to give acylmetal hydride. If subsequent decarbonylation is suppressed, hydroacylation of olefin can proceed. Cyclometalation is one of the promising ways to suppress decarbonylation. In this account, some of the work on chelation-assisted hydroacylation is reviewed. The mechanistic studies are presented as stoichiometric hydroacylation. Catalytic reactions with various substrates are also discussed.
All Science Journal Classification (ASJC) codes
- Organic Chemistry