Chemical synthesis of cyclic galactooligofuranosides isolated from enzymatic degradation products of cell wall arabinogalactan of Mycobacterium tuberculosis

Soo Kim Kwan, Bo Young Lee, Ho Yoon Sung, Jin Jeon Hyo, Yuel Baek Ju, Kyu-Sung Jeong

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

(Chemical Equation Presented) Synthesis of cyclic tetra-, hexa- and octasaccharides containing alternating (1→5)-β- and (1→6)-β-galactofuranosyl linkages has been achieved by intramolecular cycloglycosylation of corresponding linear sugars and by cyclooligomerization of 1,6-linked and 1,5-linked disaccharides. In particular, cyclooligomerization of the (1→6)-β-galactofuranosyl disaccharide provides an efficient way to secure all three cyclic sugars in one operation.

Original languageEnglish
Pages (from-to)2373-2376
Number of pages4
JournalOrganic Letters
Volume10
Issue number12
DOIs
Publication statusPublished - 2008 Dec 1

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tuberculosis
Disaccharides
sugars
Mycobacterium tuberculosis
Sugars
Cell Wall
Cells
degradation
Degradation
synthesis
products
linkages
arabinogalactan

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Kwan, Soo Kim ; Lee, Bo Young ; Sung, Ho Yoon ; Hyo, Jin Jeon ; Ju, Yuel Baek ; Jeong, Kyu-Sung. / Chemical synthesis of cyclic galactooligofuranosides isolated from enzymatic degradation products of cell wall arabinogalactan of Mycobacterium tuberculosis. In: Organic Letters. 2008 ; Vol. 10, No. 12. pp. 2373-2376.
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Chemical synthesis of cyclic galactooligofuranosides isolated from enzymatic degradation products of cell wall arabinogalactan of Mycobacterium tuberculosis. / Kwan, Soo Kim; Lee, Bo Young; Sung, Ho Yoon; Hyo, Jin Jeon; Ju, Yuel Baek; Jeong, Kyu-Sung.

In: Organic Letters, Vol. 10, No. 12, 01.12.2008, p. 2373-2376.

Research output: Contribution to journalArticle

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