Chemical synthesis of cyclic galactooligofuranosides isolated from enzymatic degradation products of cell wall arabinogalactan of Mycobacterium tuberculosis

Soo Kim Kwan, Bo Young Lee, Ho Yoon Sung, Jin Jeon Hyo, Yuel Baek Ju, Kyu-Sung Jeong

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(Chemical Equation Presented) Synthesis of cyclic tetra-, hexa- and octasaccharides containing alternating (1→5)-β- and (1→6)-β-galactofuranosyl linkages has been achieved by intramolecular cycloglycosylation of corresponding linear sugars and by cyclooligomerization of 1,6-linked and 1,5-linked disaccharides. In particular, cyclooligomerization of the (1→6)-β-galactofuranosyl disaccharide provides an efficient way to secure all three cyclic sugars in one operation.

Original languageEnglish
Pages (from-to)2373-2376
Number of pages4
JournalOrganic Letters
Issue number12
Publication statusPublished - 2008 Dec 1


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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