Abstract
Two types of maleimidosugars as thiol-selective carbohydrates, 1-maleimidosugars and acetyl-linked maleimidosugars, were efficiently synthesized. They were coupled to glutathione, Fas peptide and bovine serium albumin (BSA) to prepare the corresponding glycosylated peptides and a protein via stable thioether linkages in a chemoselective manner.
| Original language | English |
|---|---|
| Pages (from-to) | 1325-1328 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 42 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2001 Feb 12 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Chemoselective ligation of maleimidosugars to peptides/protein for the preparation of neoglycopeptides/neoglycoprotein. / Shin, Injae; Jung, Hyuk Jun; Lee, Myung Ryul.
In: Tetrahedron Letters, Vol. 42, No. 7, 12.02.2001, p. 1325-1328.Research output: Contribution to journal › Article
TY - JOUR
T1 - Chemoselective ligation of maleimidosugars to peptides/protein for the preparation of neoglycopeptides/neoglycoprotein
AU - Shin, Injae
AU - Jung, Hyuk Jun
AU - Lee, Myung Ryul
PY - 2001/2/12
Y1 - 2001/2/12
N2 - Two types of maleimidosugars as thiol-selective carbohydrates, 1-maleimidosugars and acetyl-linked maleimidosugars, were efficiently synthesized. They were coupled to glutathione, Fas peptide and bovine serium albumin (BSA) to prepare the corresponding glycosylated peptides and a protein via stable thioether linkages in a chemoselective manner.
AB - Two types of maleimidosugars as thiol-selective carbohydrates, 1-maleimidosugars and acetyl-linked maleimidosugars, were efficiently synthesized. They were coupled to glutathione, Fas peptide and bovine serium albumin (BSA) to prepare the corresponding glycosylated peptides and a protein via stable thioether linkages in a chemoselective manner.
UR - http://www.scopus.com/inward/record.url?scp=0035847491&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035847491&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(00)02286-3
DO - 10.1016/S0040-4039(00)02286-3
M3 - Article
VL - 42
SP - 1325
EP - 1328
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 7
ER -