Abstract
Two types of maleimidosugars as thiol-selective carbohydrates, 1-maleimidosugars and acetyl-linked maleimidosugars, were efficiently synthesized. They were coupled to glutathione, Fas peptide and bovine serium albumin (BSA) to prepare the corresponding glycosylated peptides and a protein via stable thioether linkages in a chemoselective manner.
| Original language | English |
|---|---|
| Pages (from-to) | 1325-1328 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 42 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2001 Feb 12 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Shin, I., Jung, H. J., & Lee, M. R. (2001). Chemoselective ligation of maleimidosugars to peptides/protein for the preparation of neoglycopeptides/neoglycoprotein. Tetrahedron Letters, 42(7), 1325-1328. https://doi.org/10.1016/S0040-4039(00)02286-3