TY - JOUR
T1 - Chest ct abnormalities in covid-19
T2 - A systematic review
AU - Ghayda, Ramy Abou
AU - Lee, Keum Hwa
AU - Kim, Jae Seok
AU - Lee, Seul
AU - Hong, Sung Hwi
AU - Kim, Kyeong Seok
AU - Kim, Kyeong Eon
AU - Seok, Jinhyn
AU - Kim, Hajeong
AU - Seo, Jangsuk
AU - Lee, Seungmin
AU - Koyanagi, Ai
AU - Jacob, Louis
AU - Smith, Lee
AU - Li, Han
AU - Kronbichler, Andreas
AU - Shin, Jae Il
N1 - Publisher Copyright:
© The author(s).
PY - 2021
Y1 - 2021
N2 - Computed tomography (CT) of the chest is one of the main diagnositic tools for coronavirus disease 2019 (COVID-19) infection. To document the chest CT findings in patients with confirmed COVID-19 and their association with the clinical severity, we searched related literatures through PubMed, MEDLINE, Embase, Web of Science (inception to May 4, 2020) and reviewed reference lists of previous systematic reviews. A total of 31 case reports (3768 patients) on CT findings of COVID-19 were included. The most common comorbid conditions were hypertension (18.4%) and diabetes mellitus (8.3%). The most common symptom was fever (78.7%), followed by cough (60.2%). It took an average of 5.6 days from symptom onset to admission. The most common chest CT finding was vascular enlargement (84.8%), followed by ground-glass opacity (GGO) (60.1%), air-bronchogram (47.8%), and consolidation (41.4%). Most lung lesions were located in the lung periphery (72.2%) and involved bilateral lung (76%). Most patients showed normal range of laboratory findings such as white blood cell count (96.4%) and lymphocyte (87.2%). Compared to previous published meta-analyses, our study is the first to summarize the different radiologic characteristics of chest CT in a total of 3768 COVID-19 patients by compiling case series studies. A comprehensive diagnostic approach should be adopted for patients with known COVID-19, suspected cases, and for exposed individuals.
AB - Computed tomography (CT) of the chest is one of the main diagnositic tools for coronavirus disease 2019 (COVID-19) infection. To document the chest CT findings in patients with confirmed COVID-19 and their association with the clinical severity, we searched related literatures through PubMed, MEDLINE, Embase, Web of Science (inception to May 4, 2020) and reviewed reference lists of previous systematic reviews. A total of 31 case reports (3768 patients) on CT findings of COVID-19 were included. The most common comorbid conditions were hypertension (18.4%) and diabetes mellitus (8.3%). The most common symptom was fever (78.7%), followed by cough (60.2%). It took an average of 5.6 days from symptom onset to admission. The most common chest CT finding was vascular enlargement (84.8%), followed by ground-glass opacity (GGO) (60.1%), air-bronchogram (47.8%), and consolidation (41.4%). Most lung lesions were located in the lung periphery (72.2%) and involved bilateral lung (76%). Most patients showed normal range of laboratory findings such as white blood cell count (96.4%) and lymphocyte (87.2%). Compared to previous published meta-analyses, our study is the first to summarize the different radiologic characteristics of chest CT in a total of 3768 COVID-19 patients by compiling case series studies. A comprehensive diagnostic approach should be adopted for patients with known COVID-19, suspected cases, and for exposed individuals.
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U2 - 10.7150/ijms.50568
DO - 10.7150/ijms.50568
M3 - Article
C2 - 34522166
AN - SCOPUS:85115817188
SN - 1449-1907
VL - 18
SP - 3395
EP - 3402
JO - International Journal of Medical Sciences
JF - International Journal of Medical Sciences
IS - 15
ER -
