Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor

Seung Ah Lee, Xiaoze Ou, J. Eugene Lee, Changhuei Yang

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We demonstrate a silo-filter (SF) complementary metal-oxide semiconductor (CMOS) image sensor for a chip-scale fluorescence microscope. The extruded pixel design with metal walls between neighboring pixels guides fluorescence emission through the thick absorptive filter to the photodiode of a pixel. Our prototype device achieves 13 μm resolution over a wide field of view (4.8 mm × 4.4 mm). We demonstrate bright-field and fluorescence longitudinal imaging of living cells in a compact, low-cost configuration.

Original languageEnglish
Pages (from-to)1817-1819
Number of pages3
JournalOptics Letters
Volume38
Issue number11
DOIs
Publication statusPublished - 2013 Jun 1

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CMOS
pixels
chips
microscopes
filters
fluorescence
sensors
field of view
photodiodes
prototypes
configurations
metals

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics

Cite this

Lee, Seung Ah ; Ou, Xiaoze ; Lee, J. Eugene ; Yang, Changhuei. / Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor. In: Optics Letters. 2013 ; Vol. 38, No. 11. pp. 1817-1819.
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Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor. / Lee, Seung Ah; Ou, Xiaoze; Lee, J. Eugene; Yang, Changhuei.

In: Optics Letters, Vol. 38, No. 11, 01.06.2013, p. 1817-1819.

Research output: Contribution to journalArticle

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