Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor

Seung Ah Lee; Xiaoze Ou; J. Eugene Lee; Changhuei Yang

doi:10.1364/OL.38.001817

Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor

Seung Ah Lee, Xiaoze Ou, J. Eugene Lee, Changhuei Yang

Department of Electrical and Electronic Engineering

Research output: Contribution to journal › Article

17 Citations (Scopus)

Abstract

We demonstrate a silo-filter (SF) complementary metal-oxide semiconductor (CMOS) image sensor for a chip-scale fluorescence microscope. The extruded pixel design with metal walls between neighboring pixels guides fluorescence emission through the thick absorptive filter to the photodiode of a pixel. Our prototype device achieves 13 μm resolution over a wide field of view (4.8 mm × 4.4 mm). We demonstrate bright-field and fluorescence longitudinal imaging of living cells in a compact, low-cost configuration.

Original language	English
Pages (from-to)	1817-1819
Number of pages	3
Journal	Optics Letters
Volume	38
Issue number	11
DOIs	https://doi.org/10.1364/OL.38.001817
Publication status	Published - 2013 Jun 1

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All Science Journal Classification (ASJC) codes

Atomic and Molecular Physics, and Optics

Cite this

Lee, S. A., Ou, X., Lee, J. E., & Yang, C. (2013). Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor. Optics Letters, 38(11), 1817-1819. https://doi.org/10.1364/OL.38.001817

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10.1364/OL.38.001817