Abstract
We report the chiroptical signature and binding interactions of cationic (meso-tetrakis(4-N-methylptridyl)porphyrin, 2HT4) and anionic (meso-tetrakis(4-sulfonatophenyl)porphyrin, 2HTPPS) porphyrins and their zinc(II) and nickel(II) derivatives (ZnT4, ZnTPPS, NiT4, and NiTPPS) with right-handed B-form and two forms of left-handed Z-form of alternating guanine-cytosine polydeoxynucleotide poly(dG-dC)2. NiTPPS is able to spectroscopically discriminate between spermine-induced Z-DNA and Co(III)-induced Z-DNA via new induced circular dichroism signal in the visible region of the electromagnetic spectrum.
Original language | English |
---|---|
Pages (from-to) | 1-6 |
Number of pages | 6 |
Journal | Journal of Inorganic Biochemistry |
Volume | 127 |
DOIs | |
Publication status | Published - 2013 |
Bibliographical note
Funding Information:This research was supported by University of Wyoming start-up funds. AD'U thanks University of Catania for financial support.
All Science Journal Classification (ASJC) codes
- Biochemistry
- Inorganic Chemistry