Chlorhexidine-releasing orthodontic elastomerics

Hyun Sun Jeon, Choong Ho Choi, Si Mook Kang, Ho Keun Kwon, Baek Il Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The aim of this study was to identify the best combination of chlorhexidine (CHX) with orthodontic elastomerics for prevention of oral disease in orthodontic patients. We used ethyl cellulose (EC) as the polymer, and experimental groups were divided into five groups according to differences in solvent (i.e., ethanol; EtOH, dichloromethane; DCM). CHX release from the coated elastomerics was evaluated with a UV spectrophotometer and observed by scanning electron microscope (SEM). The antimicrobial release increased over time for 48 h in Group 3 (CDA+EC+30% EtOH/70% DCM), exhibiting the longest sustained-release characteristics (p<0.001). It also showed the highest antimicrobial properties, which was confirmed by inhibition zone testing using S. mutans (p<0.05). All groups were not affected when tensile force was tested in the coated elastomerics. We conclude that the antibacterial effect of CHX can be adjusted according to combinations of polymers and solvents. Group 3 exhibited the best substantivity and antimicrobial properties.

Original languageEnglish
Pages (from-to)321-326
Number of pages6
JournalDental Materials Journal
Volume34
Issue number3
DOIs
Publication statusPublished - 2015 Apr 23

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Dentistry(all)

Fingerprint Dive into the research topics of 'Chlorhexidine-releasing orthodontic elastomerics'. Together they form a unique fingerprint.

  • Cite this