Cholesterol biosynthesis from lanosterol: A concerted role for Sp1 and NF-Y-binding sites for sterol-mediated regulation of rat 7-dehydrocholesterol reductase gene expression

Medicine & Life Sciences

• 7-dehydrocholesterol reductase 100%
• Lanosterol 88%
• Sterols 65%
• Binding Sites 43%
• Cholesterol 41%
• Gene Expression 33%
• Genes 13%
• Enzymes 12%
• Smith-Lemli-Opitz Syndrome 9%
• Deoxyribonucleases 7%
• 5' Flanking Region 6%
• Electrophoretic Mobility Shift Assay 6%
• Regulator Genes 5%
• Liver 5%
• Luciferases 5%

Chemistry

• Lanosterol 80%
• Sterol 61%
• Cholesterol 50%
• Biosynthesis 47%
• Binding Site 26%
• Enzyme Activity 15%
• Protein 7%