Abstract
The classification, size and activity of choroidal neovascularization (CNV) by optical coherence tomography (OCT) were compared with those obtained by fluorescein angiography (FA) and Indocyanine green angiography (ICG). This study included 32 patients (32 eyes) diagnosed as having CNV. The etiology of CNV was found to be age-related macular degeneration (AMD) or non-AMD. Patients were studied retrospectively by FA, ICG, and OCT. Of the 13 eyes with AMD, the boundary of the lesion could not be defined using FA in 7 patients. Among the 7 poorly defined CNV cases by FA, the identification of the boundary was possible in one case by OCT. The mean diameter of the classic well-defined lesions was 3500 ± 421 μm by FA, 2624 ± 1044 μm by ICG, and 1927 ± 1272 μm by OCT. The size of the CNV by OCT was always smaller than by FA or ICG. Of the 19 eyes with Non-AMD, the boundary of the lesion could not be defined by FA in 5 patients. Among the 5 poorly defined cases by FA, the identification of the boundary was possible in 3 cases by OCT. The mean diameter of the well-defined CNV lesions was 2153 ± 759 μm by FA, 1929 ± 673 μm by ICG, and 1322 ± 566 μm by OCT. Retinal thickness, which represents retinal edema, was found to be proportional to lesion size, although the relationship was not statistically significant. Regardless of CNV type, FA, ICG and OCT used in combination increase the specificity of diagnosis if their findings are compared.
| Original language | English |
|---|---|
| Pages (from-to) | 821-827 |
| Number of pages | 7 |
| Journal | Yonsei Medical Journal |
| Volume | 44 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2003 Oct 30 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
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Choroidal neovascularization characteristics and its size in optical coherence tomography. / Kim, Seung Gab; Lee, Sungchul; Seong, Youl Seok; Kim, Sun Woong; Kwon, Oh Woong.
In: Yonsei Medical Journal, Vol. 44, No. 5, 30.10.2003, p. 821-827.Research output: Contribution to journal › Article
TY - JOUR
T1 - Choroidal neovascularization characteristics and its size in optical coherence tomography
AU - Kim, Seung Gab
AU - Lee, Sungchul
AU - Seong, Youl Seok
AU - Kim, Sun Woong
AU - Kwon, Oh Woong
PY - 2003/10/30
Y1 - 2003/10/30
N2 - The classification, size and activity of choroidal neovascularization (CNV) by optical coherence tomography (OCT) were compared with those obtained by fluorescein angiography (FA) and Indocyanine green angiography (ICG). This study included 32 patients (32 eyes) diagnosed as having CNV. The etiology of CNV was found to be age-related macular degeneration (AMD) or non-AMD. Patients were studied retrospectively by FA, ICG, and OCT. Of the 13 eyes with AMD, the boundary of the lesion could not be defined using FA in 7 patients. Among the 7 poorly defined CNV cases by FA, the identification of the boundary was possible in one case by OCT. The mean diameter of the classic well-defined lesions was 3500 ± 421 μm by FA, 2624 ± 1044 μm by ICG, and 1927 ± 1272 μm by OCT. The size of the CNV by OCT was always smaller than by FA or ICG. Of the 19 eyes with Non-AMD, the boundary of the lesion could not be defined by FA in 5 patients. Among the 5 poorly defined cases by FA, the identification of the boundary was possible in 3 cases by OCT. The mean diameter of the well-defined CNV lesions was 2153 ± 759 μm by FA, 1929 ± 673 μm by ICG, and 1322 ± 566 μm by OCT. Retinal thickness, which represents retinal edema, was found to be proportional to lesion size, although the relationship was not statistically significant. Regardless of CNV type, FA, ICG and OCT used in combination increase the specificity of diagnosis if their findings are compared.
AB - The classification, size and activity of choroidal neovascularization (CNV) by optical coherence tomography (OCT) were compared with those obtained by fluorescein angiography (FA) and Indocyanine green angiography (ICG). This study included 32 patients (32 eyes) diagnosed as having CNV. The etiology of CNV was found to be age-related macular degeneration (AMD) or non-AMD. Patients were studied retrospectively by FA, ICG, and OCT. Of the 13 eyes with AMD, the boundary of the lesion could not be defined using FA in 7 patients. Among the 7 poorly defined CNV cases by FA, the identification of the boundary was possible in one case by OCT. The mean diameter of the classic well-defined lesions was 3500 ± 421 μm by FA, 2624 ± 1044 μm by ICG, and 1927 ± 1272 μm by OCT. The size of the CNV by OCT was always smaller than by FA or ICG. Of the 19 eyes with Non-AMD, the boundary of the lesion could not be defined by FA in 5 patients. Among the 5 poorly defined cases by FA, the identification of the boundary was possible in 3 cases by OCT. The mean diameter of the well-defined CNV lesions was 2153 ± 759 μm by FA, 1929 ± 673 μm by ICG, and 1322 ± 566 μm by OCT. Retinal thickness, which represents retinal edema, was found to be proportional to lesion size, although the relationship was not statistically significant. Regardless of CNV type, FA, ICG and OCT used in combination increase the specificity of diagnosis if their findings are compared.
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U2 - 10.3349/ymj.2003.44.5.821
DO - 10.3349/ymj.2003.44.5.821
M3 - Article
VL - 44
SP - 821
EP - 827
JO - Yonsei Medical Journal
JF - Yonsei Medical Journal
SN - 0513-5796
IS - 5
ER -