Cis-2-Aminocyclohex-4-enecarboxylic acid as a new building block of helical foldamers

Sunmi Kwon, Philjae Kang, Moon Gun Choi, Soo Hyuk Choi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

cis-2-Aminocyclohex-4-enecarboxylic acid (cis-ACHE) is a conformationally constrained β-amino acid. We showed that the conformational preference of a cis-ACHE residue is similar to that of cis-2-aminocyclohexanecarboxylic acid. α/β-Peptides that consist of the alternation of (1S,2R)-cis-ACHE and l-alanine adopted 11/9-helical conformations in solution and in the crystal state.

Original languageEnglish
Pages (from-to)3221-3224
Number of pages4
JournalNew Journal of Chemistry
Volume39
Issue number5
DOIs
Publication statusPublished - 2015 May 1

Fingerprint

Acids
Alanine
Conformations
Peptides
Amino acids
Amino Acids
Crystals
2-aminocyclohexanecarboxylic acid

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Materials Chemistry

Cite this

Kwon, Sunmi ; Kang, Philjae ; Choi, Moon Gun ; Choi, Soo Hyuk. / Cis-2-Aminocyclohex-4-enecarboxylic acid as a new building block of helical foldamers. In: New Journal of Chemistry. 2015 ; Vol. 39, No. 5. pp. 3221-3224.
@article{8f8b09731a814b3582d55fe8fb7f65bc,
title = "Cis-2-Aminocyclohex-4-enecarboxylic acid as a new building block of helical foldamers",
abstract = "cis-2-Aminocyclohex-4-enecarboxylic acid (cis-ACHE) is a conformationally constrained β-amino acid. We showed that the conformational preference of a cis-ACHE residue is similar to that of cis-2-aminocyclohexanecarboxylic acid. α/β-Peptides that consist of the alternation of (1S,2R)-cis-ACHE and l-alanine adopted 11/9-helical conformations in solution and in the crystal state.",
author = "Sunmi Kwon and Philjae Kang and Choi, {Moon Gun} and Choi, {Soo Hyuk}",
year = "2015",
month = "5",
day = "1",
doi = "10.1039/c4nj02056a",
language = "English",
volume = "39",
pages = "3221--3224",
journal = "New Journal of Chemistry",
issn = "1144-0546",
publisher = "Royal Society of Chemistry",
number = "5",

}

Cis-2-Aminocyclohex-4-enecarboxylic acid as a new building block of helical foldamers. / Kwon, Sunmi; Kang, Philjae; Choi, Moon Gun; Choi, Soo Hyuk.

In: New Journal of Chemistry, Vol. 39, No. 5, 01.05.2015, p. 3221-3224.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Cis-2-Aminocyclohex-4-enecarboxylic acid as a new building block of helical foldamers

AU - Kwon, Sunmi

AU - Kang, Philjae

AU - Choi, Moon Gun

AU - Choi, Soo Hyuk

PY - 2015/5/1

Y1 - 2015/5/1

N2 - cis-2-Aminocyclohex-4-enecarboxylic acid (cis-ACHE) is a conformationally constrained β-amino acid. We showed that the conformational preference of a cis-ACHE residue is similar to that of cis-2-aminocyclohexanecarboxylic acid. α/β-Peptides that consist of the alternation of (1S,2R)-cis-ACHE and l-alanine adopted 11/9-helical conformations in solution and in the crystal state.

AB - cis-2-Aminocyclohex-4-enecarboxylic acid (cis-ACHE) is a conformationally constrained β-amino acid. We showed that the conformational preference of a cis-ACHE residue is similar to that of cis-2-aminocyclohexanecarboxylic acid. α/β-Peptides that consist of the alternation of (1S,2R)-cis-ACHE and l-alanine adopted 11/9-helical conformations in solution and in the crystal state.

UR - http://www.scopus.com/inward/record.url?scp=84928963439&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84928963439&partnerID=8YFLogxK

U2 - 10.1039/c4nj02056a

DO - 10.1039/c4nj02056a

M3 - Article

AN - SCOPUS:84928963439

VL - 39

SP - 3221

EP - 3224

JO - New Journal of Chemistry

JF - New Journal of Chemistry

SN - 1144-0546

IS - 5

ER -