cis-2-Aminocyclohex-4-enecarboxylic acid (cis-ACHE) is a conformationally constrained β-amino acid. We showed that the conformational preference of a cis-ACHE residue is similar to that of cis-2-aminocyclohexanecarboxylic acid. α/β-Peptides that consist of the alternation of (1S,2R)-cis-ACHE and l-alanine adopted 11/9-helical conformations in solution and in the crystal state.
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© The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2015.
All Science Journal Classification (ASJC) codes
- Materials Chemistry