Clinical and anatomical factors associated with thalamic dyskinesias

M. S. Lee, Y. D. Kim, J. W. Yang, Chulhyoung Lyoo, S. H. Oh, H. S. Kim

Research output: Contribution to journalArticle

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Abstract

To define the clinical and anatomical factors associated with dyskinesias following thalamic infarction, we performed neurological examination and three-dimensional brain magnetic resonance imaging for 23 patients with thalamic infarction. We measured the total volumes and the largest diameters of the lesions on axial and coronal images. Using the atlas of human thalamus, we investigated the damaged thalamic nuclei. We compared the means of the volumes and the largest diameters of the lesions, and the frequencies of damaged thalamic nuclei between patients with and without thalamic dyskinesias. Seven (two pseudochoreoathetosis and five dystonia) of the 23 patients with thalamic infarction developed dyskinesias. No specific neurological deficits at the onset of stroke predicted the development of dyskinesias. The mean volume of the lesions of patients with dyskinesias (739 mm3) was significantly larger than that of those without dyskiensias (92.9 mm3). The means of the largest axial (11.6 mm) and coronal (10.8 mm) diameters were significantly larger in patients with dyskinesias, compared to those (axial, 7.1 mm; coronal, 6.4 mm) of patients without dyskinesias. Patients with dyskinesias had damage in the centromedian (CM) thalamic nucleus more frequently compared to those without dyskinesias. Patients with a large thalamic infarction involving the CM nucleus are more likely to develop dyskinesias.

Original languageEnglish
Pages (from-to)137-142
Number of pages6
JournalJournal of the Neurological Sciences
Volume182
Issue number2
DOIs
Publication statusPublished - 2001 Jan 1

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Dyskinesias
Infarction
Intralaminar Thalamic Nuclei
Thalamic Nuclei
Dystonia
Atlases
Neurologic Examination
Thalamus
Stroke
Magnetic Resonance Imaging

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Lee, M. S. ; Kim, Y. D. ; Yang, J. W. ; Lyoo, Chulhyoung ; Oh, S. H. ; Kim, H. S. / Clinical and anatomical factors associated with thalamic dyskinesias. In: Journal of the Neurological Sciences. 2001 ; Vol. 182, No. 2. pp. 137-142.
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Clinical and anatomical factors associated with thalamic dyskinesias. / Lee, M. S.; Kim, Y. D.; Yang, J. W.; Lyoo, Chulhyoung; Oh, S. H.; Kim, H. S.

In: Journal of the Neurological Sciences, Vol. 182, No. 2, 01.01.2001, p. 137-142.

Research output: Contribution to journalArticle

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