Clinical and Experimental Investigation of Pseudoaneurysm in the Anterior Communicating Artery Area on 3-Dimensional Time-of-Flight Cerebral Magnetic Resonance Angiography

Tae Sub Chung, Young Jun Lee, Won Suk Kang, Sei Kwon Kang, Yoon Chul Rhim, Byeong Gyu Yoo, In Kook Park

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective: To investigate the hemodynamic mechanism of pseudoaneurysm in the anterior communicating artery (AcoA) area in magnetic resonance (MR) angiography. Methods: For the clinical study, a total of 62 patients who undertook digital subtraction angiography (DSA) because of the rupture of an aneurysm originating from a location other than the AcoA area were examined with MR angiography. The relation between signal defect at the AcoA in MR angiography and anatomic variation of the anterior cerebral artery (ACA) was evaluated. For the experimental study, MR angiography and DSA were performed on elastic silicon vascular phantoms with 2 different bifurcation angles (70° and 140°). Hemodynamic factors producing signal defects were evaluated, and the results were compared by computational fluid dynamics (CFD). Results: In a clinical study, 21 of 62 patients had a hypogenetic A1 segment on either side of the ACA. Their MR angiography showed signal defects in the axilla area of the bifurcated AcoA complex in 14 patients, 7 of which could make the residual normal vessel seem to be an aneurysm. All the cases with an intact AcoA complex showed no signal defect. In an experimental study, MR angiography of vascular phantoms with broad-angle bifurcation (140°) showed signal defects at the axilla areas of bifurcation, and these were shown as turbulent flow in DSA and CFD. Phantoms with narrow-angle bifurcation (70°) did not show a significant signal defect, however. Conclusions: A hypoplastic A1 segment accompanying a broad bifurcation angle of the contralateral A1 segment may cause a pseudoaneurysm in MR angiography because of signal defect in the AcoA area.

Original languageEnglish
Pages (from-to)414-421
Number of pages8
JournalJournal of Computer Assisted Tomography
Volume28
Issue number3
DOIs
Publication statusPublished - 2004 May 1

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Cerebral Angiography
Magnetic Resonance Angiography
False Aneurysm
Arteries
Digital Subtraction Angiography
Anterior Cerebral Artery
Axilla
Hydrodynamics
Aneurysm
Blood Vessels
Hemodynamics
Anatomic Variation
Silicon
Rupture

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

@article{104afaaae922435ba75e427bd72d7f64,
title = "Clinical and Experimental Investigation of Pseudoaneurysm in the Anterior Communicating Artery Area on 3-Dimensional Time-of-Flight Cerebral Magnetic Resonance Angiography",
abstract = "Objective: To investigate the hemodynamic mechanism of pseudoaneurysm in the anterior communicating artery (AcoA) area in magnetic resonance (MR) angiography. Methods: For the clinical study, a total of 62 patients who undertook digital subtraction angiography (DSA) because of the rupture of an aneurysm originating from a location other than the AcoA area were examined with MR angiography. The relation between signal defect at the AcoA in MR angiography and anatomic variation of the anterior cerebral artery (ACA) was evaluated. For the experimental study, MR angiography and DSA were performed on elastic silicon vascular phantoms with 2 different bifurcation angles (70° and 140°). Hemodynamic factors producing signal defects were evaluated, and the results were compared by computational fluid dynamics (CFD). Results: In a clinical study, 21 of 62 patients had a hypogenetic A1 segment on either side of the ACA. Their MR angiography showed signal defects in the axilla area of the bifurcated AcoA complex in 14 patients, 7 of which could make the residual normal vessel seem to be an aneurysm. All the cases with an intact AcoA complex showed no signal defect. In an experimental study, MR angiography of vascular phantoms with broad-angle bifurcation (140°) showed signal defects at the axilla areas of bifurcation, and these were shown as turbulent flow in DSA and CFD. Phantoms with narrow-angle bifurcation (70°) did not show a significant signal defect, however. Conclusions: A hypoplastic A1 segment accompanying a broad bifurcation angle of the contralateral A1 segment may cause a pseudoaneurysm in MR angiography because of signal defect in the AcoA area.",
author = "Chung, {Tae Sub} and Lee, {Young Jun} and Kang, {Won Suk} and Kang, {Sei Kwon} and Rhim, {Yoon Chul} and Yoo, {Byeong Gyu} and Park, {In Kook}",
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Clinical and Experimental Investigation of Pseudoaneurysm in the Anterior Communicating Artery Area on 3-Dimensional Time-of-Flight Cerebral Magnetic Resonance Angiography. / Chung, Tae Sub; Lee, Young Jun; Kang, Won Suk; Kang, Sei Kwon; Rhim, Yoon Chul; Yoo, Byeong Gyu; Park, In Kook.

In: Journal of Computer Assisted Tomography, Vol. 28, No. 3, 01.05.2004, p. 414-421.

Research output: Contribution to journalArticle

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T1 - Clinical and Experimental Investigation of Pseudoaneurysm in the Anterior Communicating Artery Area on 3-Dimensional Time-of-Flight Cerebral Magnetic Resonance Angiography

AU - Chung, Tae Sub

AU - Lee, Young Jun

AU - Kang, Won Suk

AU - Kang, Sei Kwon

AU - Rhim, Yoon Chul

AU - Yoo, Byeong Gyu

AU - Park, In Kook

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N2 - Objective: To investigate the hemodynamic mechanism of pseudoaneurysm in the anterior communicating artery (AcoA) area in magnetic resonance (MR) angiography. Methods: For the clinical study, a total of 62 patients who undertook digital subtraction angiography (DSA) because of the rupture of an aneurysm originating from a location other than the AcoA area were examined with MR angiography. The relation between signal defect at the AcoA in MR angiography and anatomic variation of the anterior cerebral artery (ACA) was evaluated. For the experimental study, MR angiography and DSA were performed on elastic silicon vascular phantoms with 2 different bifurcation angles (70° and 140°). Hemodynamic factors producing signal defects were evaluated, and the results were compared by computational fluid dynamics (CFD). Results: In a clinical study, 21 of 62 patients had a hypogenetic A1 segment on either side of the ACA. Their MR angiography showed signal defects in the axilla area of the bifurcated AcoA complex in 14 patients, 7 of which could make the residual normal vessel seem to be an aneurysm. All the cases with an intact AcoA complex showed no signal defect. In an experimental study, MR angiography of vascular phantoms with broad-angle bifurcation (140°) showed signal defects at the axilla areas of bifurcation, and these were shown as turbulent flow in DSA and CFD. Phantoms with narrow-angle bifurcation (70°) did not show a significant signal defect, however. Conclusions: A hypoplastic A1 segment accompanying a broad bifurcation angle of the contralateral A1 segment may cause a pseudoaneurysm in MR angiography because of signal defect in the AcoA area.

AB - Objective: To investigate the hemodynamic mechanism of pseudoaneurysm in the anterior communicating artery (AcoA) area in magnetic resonance (MR) angiography. Methods: For the clinical study, a total of 62 patients who undertook digital subtraction angiography (DSA) because of the rupture of an aneurysm originating from a location other than the AcoA area were examined with MR angiography. The relation between signal defect at the AcoA in MR angiography and anatomic variation of the anterior cerebral artery (ACA) was evaluated. For the experimental study, MR angiography and DSA were performed on elastic silicon vascular phantoms with 2 different bifurcation angles (70° and 140°). Hemodynamic factors producing signal defects were evaluated, and the results were compared by computational fluid dynamics (CFD). Results: In a clinical study, 21 of 62 patients had a hypogenetic A1 segment on either side of the ACA. Their MR angiography showed signal defects in the axilla area of the bifurcated AcoA complex in 14 patients, 7 of which could make the residual normal vessel seem to be an aneurysm. All the cases with an intact AcoA complex showed no signal defect. In an experimental study, MR angiography of vascular phantoms with broad-angle bifurcation (140°) showed signal defects at the axilla areas of bifurcation, and these were shown as turbulent flow in DSA and CFD. Phantoms with narrow-angle bifurcation (70°) did not show a significant signal defect, however. Conclusions: A hypoplastic A1 segment accompanying a broad bifurcation angle of the contralateral A1 segment may cause a pseudoaneurysm in MR angiography because of signal defect in the AcoA area.

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