Clinical and histological aspect of erythema dyschromicum perstans in Korea: A review of 68 cases

Sung Eun Chang, Hyun Woo Kim, Jae Min Shin, Ji Hyun Lee, Jung Im Na, MiRyung Roh, Jong Hee Lee, Ga Young Lee, Joo Yeon Ko

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Abstract

Erythema dyschromicum perstans (EDP) is a hypermelanotic disorder of the idiopathic variety characterized by blue-gray macules in healthy individuals. It has been described mainly in patients from tropical areas of Central and South America. Our aim was to evaluate EDP in Korea through the analysis of retrospective case series with EDP and to describe the clinical and histopathological features. It was a retrospective study (2002-2012) of EDP confirmed by review of clinical photographs and biopsy specimens. The files of 68 patients with EDP from six tertiary medical centers in Korea were included in this study. Of the 68 patients, 29 were male and 39 female. The age of patients ranged 3-76 years (mean, 33.9). Clinically, the majority of patients had lesions on the trunk (n = 47, 69.1%); the neck was affected in 27 cases, the upper extremities in 26, the face in 22 and the lower extremities in 16. Peripheral erythematous borders were observed in 12 patients (17.6%) and 11 patients had itching sensation at the lesion. Histopathologically, dermal melanophages and pigment incontinence were the most common findings. A follow up of more than 1 year was obtained in 51 patients. Of these, only one patient experienced complete clearance without recurrence. Our study illustrates the clinical and histopathological findings of EDP in Koreans. Our multicenter data may contribute to the understanding of EDP.

Original languageEnglish
Pages (from-to)1053-1057
Number of pages5
JournalJournal of Dermatology
Volume42
Issue number11
DOIs
Publication statusPublished - 2015 Nov 1

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Erythema
Korea
Central America
South America
Pruritus
Upper Extremity
Lower Extremity
Neck
Retrospective Studies
Biopsy
Recurrence
Skin

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Chang, Sung Eun ; Kim, Hyun Woo ; Shin, Jae Min ; Lee, Ji Hyun ; Na, Jung Im ; Roh, MiRyung ; Lee, Jong Hee ; Lee, Ga Young ; Ko, Joo Yeon. / Clinical and histological aspect of erythema dyschromicum perstans in Korea : A review of 68 cases. In: Journal of Dermatology. 2015 ; Vol. 42, No. 11. pp. 1053-1057.
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Chang, SE, Kim, HW, Shin, JM, Lee, JH, Na, JI, Roh, M, Lee, JH, Lee, GY & Ko, JY 2015, 'Clinical and histological aspect of erythema dyschromicum perstans in Korea: A review of 68 cases', Journal of Dermatology, vol. 42, no. 11, pp. 1053-1057. https://doi.org/10.1111/1346-8138.13002

Clinical and histological aspect of erythema dyschromicum perstans in Korea : A review of 68 cases. / Chang, Sung Eun; Kim, Hyun Woo; Shin, Jae Min; Lee, Ji Hyun; Na, Jung Im; Roh, MiRyung; Lee, Jong Hee; Lee, Ga Young; Ko, Joo Yeon.

In: Journal of Dermatology, Vol. 42, No. 11, 01.11.2015, p. 1053-1057.

Research output: Contribution to journalArticle

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AU - Chang, Sung Eun

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AU - Na, Jung Im

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