Clinical and Molecular Perspectives of Reparative Dentin Formation: Lessons Learned from Pulp-Capping Materials and the Emerging Roles of Calcium

Minju Song; Bo Yu; Sol Kim; Marc Hayashi; Colby Smith; Suhjin Sohn; Euiseong Kim; James Lim; Richard G. Stevenson; Reuben H. Kim

doi:10.1016/j.cden.2016.08.008

Clinical and Molecular Perspectives of Reparative Dentin Formation: Lessons Learned from Pulp-Capping Materials and the Emerging Roles of Calcium

Minju Song, Bo Yu, Sol Kim, Marc Hayashi, Colby Smith, Suhjin Sohn, Euiseong Kim, James Lim, Richard G. Stevenson, Reuben H. Kim

Department of Conservative Dentistry

Research output: Contribution to journal › Review article › peer-review

37 Citations (Scopus)

Abstract

The long-term use of calcium hydroxide and the recent increase in the use of hydraulic calcium-silicate cements as direct pulp-capping materials provide important clues in terms of how reparative dentin may be induced to form a “biological seal” to protect the underlying pulp tissues. In this review article, we discuss clinical and molecular perspectives of reparative dentin formation based on evidence learned from the use of these pulp-capping materials. We also discuss the emerging role of calcium as an odontoinductive component in these pulp-capping materials.

Original language	English
Pages (from-to)	93-110
Number of pages	18
Journal	Dental Clinics of North America
Volume	61
Issue number	1
DOIs	https://doi.org/10.1016/j.cden.2016.08.008
Publication status	Published - 2017 Jan 1

Bibliographical note

Funding Information:
This study was, in part, supported by grants from NIDCR / NIH R01DE023348 ( RHK ), UCLA Faculty Research grant (RHK), and Dean’s Faculty Research Seed grant (RHK).

Publisher Copyright:
© 2016 Elsevier Inc.

All Science Journal Classification (ASJC) codes

Dentistry(all)

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10.1016/j.cden.2016.08.008

Cite this

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abstract = "The long-term use of calcium hydroxide and the recent increase in the use of hydraulic calcium-silicate cements as direct pulp-capping materials provide important clues in terms of how reparative dentin may be induced to form a “biological seal” to protect the underlying pulp tissues. In this review article, we discuss clinical and molecular perspectives of reparative dentin formation based on evidence learned from the use of these pulp-capping materials. We also discuss the emerging role of calcium as an odontoinductive component in these pulp-capping materials.",

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AU - Kim, Sol

AU - Hayashi, Marc

AU - Smith, Colby

AU - Sohn, Suhjin

AU - Kim, Euiseong

AU - Lim, James

AU - Stevenson, Richard G.

AU - Kim, Reuben H.

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Clinical and Molecular Perspectives of Reparative Dentin Formation: Lessons Learned from Pulp-Capping Materials and the Emerging Roles of Calcium

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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