Clinical and Molecular Perspectives of Reparative Dentin Formation: Lessons Learned from Pulp-Capping Materials and the Emerging Roles of Calcium

Minju Song, Bo Yu, Sol Kim, Marc Hayashi, Colby Smith, Suhjin Sohn, Euiseong Kim, James Lim, Richard G. Stevenson, Reuben H. Kim

Research output: Contribution to journalReview articlepeer-review

20 Citations (Scopus)

Abstract

The long-term use of calcium hydroxide and the recent increase in the use of hydraulic calcium-silicate cements as direct pulp-capping materials provide important clues in terms of how reparative dentin may be induced to form a “biological seal” to protect the underlying pulp tissues. In this review article, we discuss clinical and molecular perspectives of reparative dentin formation based on evidence learned from the use of these pulp-capping materials. We also discuss the emerging role of calcium as an odontoinductive component in these pulp-capping materials.

Original languageEnglish
Pages (from-to)93-110
Number of pages18
JournalDental Clinics of North America
Volume61
Issue number1
DOIs
Publication statusPublished - 2017 Jan 1

Bibliographical note

Funding Information:
This study was, in part, supported by grants from NIDCR / NIH R01DE023348 ( RHK ), UCLA Faculty Research grant (RHK), and Dean’s Faculty Research Seed grant (RHK).

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

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