Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging

Subhi J. Al'Aref; Khalil Anchouche; Gurpreet Singh; Piotr J. Slomka; Kranthi K. Kolli; Amit Kumar; Mohit Pandey; Gabriel Maliakal; Alexander R. Van Rosendael; Ashley N. Beecy; Daniel S. Berman; Jonathan Leipsic; Koen Nieman; Daniele Andreini; Gianluca Pontone; U. Joseph Schoepf; Leslee J. Shaw; Hyuk Jae Chang; Jagat Narula; Jeroen J. Bax; Yuanfang Guan; James K. Min

doi:10.1093/eurheartj/ehy404

Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging

Subhi J. Al'Aref, Khalil Anchouche, Gurpreet Singh, Piotr J. Slomka, Kranthi K. Kolli, Amit Kumar, Mohit Pandey, Gabriel Maliakal, Alexander R. Van Rosendael, Ashley N. Beecy, Daniel S. Berman, Jonathan Leipsic, Koen Nieman, Daniele Andreini, Gianluca Pontone, U. Joseph Schoepf, Leslee J. Shaw, Hyuk Jae Chang, Jagat Narula, Jeroen J. BaxYuanfang Guan, James K. Min

Department of Internal Medicine

Research output: Contribution to journal › Review article › peer-review

75 Citations (Scopus)

Abstract

Artificial intelligence (AI) has transformed key aspects of human life. Machine learning (ML), which is a subset of AI wherein machines autonomously acquire information by extracting patterns from large databases, has been increasingly used within the medical community, and specifically within the domain of cardiovascular diseases. In this review, we present a brief overview of ML methodologies that are used for the construction of inferential and predictive data-driven models. We highlight several domains of ML application such as echocardiography, electrocardiography, and recently developed non-invasive imaging modalities such as coronary artery calcium scoring and coronary computed tomography angiography. We conclude by reviewing the limitations associated with contemporary application of ML algorithms within the cardiovascular disease field.

Original language	English
Pages (from-to)	1975-1986
Number of pages	12
Journal	European heart journal
Volume	40
Issue number	24
DOIs	https://doi.org/10.1093/eurheartj/ehy404
Publication status	Published - 2019 Jun 21

Bibliographical note

Funding Information:
Conflict of interest: J.K.M. serves on the scientific advisory board of Arineta Ltd., on the speaker’s bureau of GE Healthcare, and owns equity in Cleerly Inc. U.J.S. receives institutional research support from Astellas Pharma Inc., Bayer Healthcare, GE Healthcare, Siemens and has received compensation for consulting and/or speaking from Bayer Healthcare, GE Healthcare, Guerbet LLC, HeartFlow Inc., and Siemens. J.L. is a consultant and has stock options in Circle CVI and Heartflow Inc, institutional corelab agreements with Edwards Lifesciences, Abbott, Medtronic and institutional research grant from GE Healthcare. K.N. has received unrestricted institutional research support from Siemens Healthineers, GE Healthcare, Bayer Healthcare and Heartflow Inc. D.S.B. has software royalties from Cedars-Sinai Medical Center. All other authors declared no conflict of interest.

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

Access to Document

10.1093/eurheartj/ehy404

Fingerprint Dive into the research topics of 'Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging'. Together they form a unique fingerprint.

Cite this

Al'Aref, S. J., Anchouche, K., Singh, G., Slomka, P. J., Kolli, K. K., Kumar, A., Pandey, M., Maliakal, G., Van Rosendael, A. R., Beecy, A. N., Berman, D. S., Leipsic, J., Nieman, K., Andreini, D., Pontone, G., Schoepf, U. J., Shaw, L. J., Chang, H. J., Narula, J., ... Min, J. K. (2019). Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging. European heart journal, 40(24), 1975-1986. https://doi.org/10.1093/eurheartj/ehy404

Al'Aref, Subhi J. ; Anchouche, Khalil ; Singh, Gurpreet ; Slomka, Piotr J. ; Kolli, Kranthi K. ; Kumar, Amit ; Pandey, Mohit ; Maliakal, Gabriel ; Van Rosendael, Alexander R. ; Beecy, Ashley N. ; Berman, Daniel S. ; Leipsic, Jonathan ; Nieman, Koen ; Andreini, Daniele ; Pontone, Gianluca ; Schoepf, U. Joseph ; Shaw, Leslee J. ; Chang, Hyuk Jae ; Narula, Jagat ; Bax, Jeroen J. ; Guan, Yuanfang ; Min, James K. / Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging. In: European heart journal. 2019 ; Vol. 40, No. 24. pp. 1975-1986.

@article{e16ce90946d343d88d03b8d177fba3e8,

title = "Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging",

abstract = "Artificial intelligence (AI) has transformed key aspects of human life. Machine learning (ML), which is a subset of AI wherein machines autonomously acquire information by extracting patterns from large databases, has been increasingly used within the medical community, and specifically within the domain of cardiovascular diseases. In this review, we present a brief overview of ML methodologies that are used for the construction of inferential and predictive data-driven models. We highlight several domains of ML application such as echocardiography, electrocardiography, and recently developed non-invasive imaging modalities such as coronary artery calcium scoring and coronary computed tomography angiography. We conclude by reviewing the limitations associated with contemporary application of ML algorithms within the cardiovascular disease field.",

author = "Al'Aref, {Subhi J.} and Khalil Anchouche and Gurpreet Singh and Slomka, {Piotr J.} and Kolli, {Kranthi K.} and Amit Kumar and Mohit Pandey and Gabriel Maliakal and {Van Rosendael}, {Alexander R.} and Beecy, {Ashley N.} and Berman, {Daniel S.} and Jonathan Leipsic and Koen Nieman and Daniele Andreini and Gianluca Pontone and Schoepf, {U. Joseph} and Shaw, {Leslee J.} and Chang, {Hyuk Jae} and Jagat Narula and Bax, {Jeroen J.} and Yuanfang Guan and Min, {James K.}",

note = "Funding Information: Conflict of interest: J.K.M. serves on the scientific advisory board of Arineta Ltd., on the speaker{\textquoteright}s bureau of GE Healthcare, and owns equity in Cleerly Inc. U.J.S. receives institutional research support from Astellas Pharma Inc., Bayer Healthcare, GE Healthcare, Siemens and has received compensation for consulting and/or speaking from Bayer Healthcare, GE Healthcare, Guerbet LLC, HeartFlow Inc., and Siemens. J.L. is a consultant and has stock options in Circle CVI and Heartflow Inc, institutional corelab agreements with Edwards Lifesciences, Abbott, Medtronic and institutional research grant from GE Healthcare. K.N. has received unrestricted institutional research support from Siemens Healthineers, GE Healthcare, Bayer Healthcare and Heartflow Inc. D.S.B. has software royalties from Cedars-Sinai Medical Center. All other authors declared no conflict of interest.",

year = "2019",

month = jun,

day = "21",

doi = "10.1093/eurheartj/ehy404",

language = "English",

volume = "40",

pages = "1975--1986",

journal = "European Heart Journal",

issn = "0195-668X",

publisher = "Oxford University Press",

number = "24",

}

Al'Aref, SJ, Anchouche, K, Singh, G, Slomka, PJ, Kolli, KK, Kumar, A, Pandey, M, Maliakal, G, Van Rosendael, AR, Beecy, AN, Berman, DS, Leipsic, J, Nieman, K, Andreini, D, Pontone, G, Schoepf, UJ, Shaw, LJ, Chang, HJ, Narula, J, Bax, JJ, Guan, Y & Min, JK 2019, 'Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging', European heart journal, vol. 40, no. 24, pp. 1975-1986. https://doi.org/10.1093/eurheartj/ehy404

Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging. / Al'Aref, Subhi J.; Anchouche, Khalil; Singh, Gurpreet; Slomka, Piotr J.; Kolli, Kranthi K.; Kumar, Amit; Pandey, Mohit; Maliakal, Gabriel; Van Rosendael, Alexander R.; Beecy, Ashley N.; Berman, Daniel S.; Leipsic, Jonathan; Nieman, Koen; Andreini, Daniele; Pontone, Gianluca; Schoepf, U. Joseph; Shaw, Leslee J.; Chang, Hyuk Jae; Narula, Jagat; Bax, Jeroen J.; Guan, Yuanfang; Min, James K.

In: European heart journal, Vol. 40, No. 24, 21.06.2019, p. 1975-1986.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging

AU - Al'Aref, Subhi J.

AU - Anchouche, Khalil

AU - Singh, Gurpreet

AU - Slomka, Piotr J.

AU - Kolli, Kranthi K.

AU - Kumar, Amit

AU - Pandey, Mohit

AU - Maliakal, Gabriel

AU - Van Rosendael, Alexander R.

AU - Beecy, Ashley N.

AU - Berman, Daniel S.

AU - Leipsic, Jonathan

AU - Nieman, Koen

AU - Andreini, Daniele

AU - Pontone, Gianluca

AU - Schoepf, U. Joseph

AU - Shaw, Leslee J.

AU - Chang, Hyuk Jae

AU - Narula, Jagat

AU - Bax, Jeroen J.

AU - Guan, Yuanfang

AU - Min, James K.

N1 - Funding Information: Conflict of interest: J.K.M. serves on the scientific advisory board of Arineta Ltd., on the speaker’s bureau of GE Healthcare, and owns equity in Cleerly Inc. U.J.S. receives institutional research support from Astellas Pharma Inc., Bayer Healthcare, GE Healthcare, Siemens and has received compensation for consulting and/or speaking from Bayer Healthcare, GE Healthcare, Guerbet LLC, HeartFlow Inc., and Siemens. J.L. is a consultant and has stock options in Circle CVI and Heartflow Inc, institutional corelab agreements with Edwards Lifesciences, Abbott, Medtronic and institutional research grant from GE Healthcare. K.N. has received unrestricted institutional research support from Siemens Healthineers, GE Healthcare, Bayer Healthcare and Heartflow Inc. D.S.B. has software royalties from Cedars-Sinai Medical Center. All other authors declared no conflict of interest.

PY - 2019/6/21

Y1 - 2019/6/21

N2 - Artificial intelligence (AI) has transformed key aspects of human life. Machine learning (ML), which is a subset of AI wherein machines autonomously acquire information by extracting patterns from large databases, has been increasingly used within the medical community, and specifically within the domain of cardiovascular diseases. In this review, we present a brief overview of ML methodologies that are used for the construction of inferential and predictive data-driven models. We highlight several domains of ML application such as echocardiography, electrocardiography, and recently developed non-invasive imaging modalities such as coronary artery calcium scoring and coronary computed tomography angiography. We conclude by reviewing the limitations associated with contemporary application of ML algorithms within the cardiovascular disease field.

AB - Artificial intelligence (AI) has transformed key aspects of human life. Machine learning (ML), which is a subset of AI wherein machines autonomously acquire information by extracting patterns from large databases, has been increasingly used within the medical community, and specifically within the domain of cardiovascular diseases. In this review, we present a brief overview of ML methodologies that are used for the construction of inferential and predictive data-driven models. We highlight several domains of ML application such as echocardiography, electrocardiography, and recently developed non-invasive imaging modalities such as coronary artery calcium scoring and coronary computed tomography angiography. We conclude by reviewing the limitations associated with contemporary application of ML algorithms within the cardiovascular disease field.

UR - http://www.scopus.com/inward/record.url?scp=85068474187&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85068474187&partnerID=8YFLogxK

U2 - 10.1093/eurheartj/ehy404

DO - 10.1093/eurheartj/ehy404

M3 - Review article

C2 - 30060039

AN - SCOPUS:85068474187

VL - 40

SP - 1975

EP - 1986

JO - European Heart Journal

JF - European Heart Journal

SN - 0195-668X

IS - 24

ER -