Clinical characteristics and outcomes of acute st-segment elevation myocardial infarction in younger Korean adults

Seung Hun Lee, Ju Han Kim, Myung Ho Jeong, Hyukjin Park, Yun Ah Jeong, Youngkeun Ahn, Jong Hyun Kim, Shung Chull Chae, Young Jo Kim, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Donghoon Choi, Myeong Chan Cho, Chong Jin Kim, Ki Bae Seung, Wook Sung Chung, Yang Soo Jang, Jeong Gwan Cho, Jong Chun ParkSeung Jung Park

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Abstract

Background and Objectives: This study aims to investigate the clinical features, angiographic findings, and outcomes of younger Korean ST-segment elevation myocardial infarction (STEMI) patients. Subjects and Methods: We analyzed major adverse cardiac events (MACE) in the Korea Acute Myocardial Infarction Registry from November 2005 to October 2010. The registered patients were divided into two groups; young age group (<65 years) and old age group (≥65 years). Results: The young age group included 5281 patients (age, 53±7.8 years), and the old age group included 4896 patients (age, 74.3±6.5 years). Male gender, smoking, family history, dyslipidemia, and metabolic syndrome were more frequently observed in the young age group than in the old age group (89.5% vs. 59.3%, p<0.001; 77.3% vs. 47.2%, p<0.001; 11% vs. 4.6%, p<0.001; 11.2% vs. 7.7%, p<0.001; 67.6% vs. 62.9%, p<0.001). Most of the young Korean adults with STEMI complained of typical chest pain (89.8%), and they had a shorter symptomto-door time (12±53.2 hours vs. 17.3±132 hours, p=0.010). The young age group showed a favorable prognosis, which was represented by the MACE, compared with the old age group at one month (1.8% vs. 2.8%, p=0.028), six months (6.8% vs. 8.2%, p<0.001), and twelve months (10.1% vs. 11.9%, p=0.025). However, there was no significant difference in the adjusted MACE rate at one month {hazard ratio (HR) 0.95, 95% confidence interval (CI) 0.60-1.51, p=0.828} and twelve months (HR 0.86, 95% CI 0.68-1.10, p=0.233). Conclusion: Younger Korean adults with STEMI have clinical outcomes similar to old aged patients, and therefore, they should be treated intensively like the elderly patients.

Original languageEnglish
Pages (from-to)275-284
Number of pages10
JournalKorean Circulation Journal
Volume45
Issue number4
DOIs
Publication statusPublished - 2015 Jul 1

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All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Lee, S. H., Kim, J. H., Jeong, M. H., Park, H., Jeong, Y. A., Ahn, Y., Kim, J. H., Chae, S. C., Kim, Y. J., Hur, S. H., Seong, I. W., Hong, T. J., Choi, D., Cho, M. C., Kim, C. J., Seung, K. B., Chung, W. S., Jang, Y. S., Cho, J. G., ... Park, S. J. (2015). Clinical characteristics and outcomes of acute st-segment elevation myocardial infarction in younger Korean adults. Korean Circulation Journal, 45(4), 275-284. https://doi.org/10.4070/kcj.2015.45.4.275