Clinical characteristics and outcomes of juvenile and adult dermatomyositis

Sang Jun Na, Seung Min Kim, Il Nam Sunwoo, Young Chul Choi

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Dermatomyositis (DM) is an idiopathic inflammatory myopathy with bimodal onset age distribution. The age of onset is between 5-18 yr in juvenile DM and 45-64 yr in adult DM. DM has a distinct clinical manifestation characterized by proximal muscle weakness, skin rash, extramuscular manifestations (joint contracture, dysphagia, cardiac disturbances, pulmonary symptoms, subcutaneous calcifications), and associated disorders (connective tissue disease, systemic autoimmune diseases, malignancy). The pathogenesis of juvenile and adult DM is presumably similar but there are important differences in some of the clinical manifestations, associated disorders, and outcomes. In this study, we investigated the clinical characteristics and outcomes of 16 patients with juvenile DM and 48 with adult DM. This study recognizes distinctive characteristics of juvenile DM such as higher frequency of neck muscle involvement, subcutaneous calcifications, and better outcomes.

Original languageEnglish
Pages (from-to)715-721
Number of pages7
JournalJournal of Korean medical science
Volume24
Issue number4
DOIs
Publication statusPublished - 2009 Aug 1

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Dermatomyositis
Neck Muscles
Myositis
Connective Tissue Diseases
Age Distribution
Muscle Weakness
Contracture
Deglutition Disorders
Exanthema
Age of Onset
Autoimmune Diseases
Joints
Lung
Juvenile dermatomyositis
Neoplasms

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Na, Sang Jun ; Kim, Seung Min ; Sunwoo, Il Nam ; Choi, Young Chul. / Clinical characteristics and outcomes of juvenile and adult dermatomyositis. In: Journal of Korean medical science. 2009 ; Vol. 24, No. 4. pp. 715-721.
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Clinical characteristics and outcomes of juvenile and adult dermatomyositis. / Na, Sang Jun; Kim, Seung Min; Sunwoo, Il Nam; Choi, Young Chul.

In: Journal of Korean medical science, Vol. 24, No. 4, 01.08.2009, p. 715-721.

Research output: Contribution to journalArticle

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