Clinical Characteristics and Prognostic Factors in Ankylosing Spondylitis Associated Uveitis

Ji Hwan Lee, Moonjung Choi, Tyler Hyung Taek Rim, Sung Chul Lee, Christopher Seungkyu Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: To identify the clinical features and prognostic factors of uveitis associated with ankylosing spondylitis (AS). Methods: This retrospective, interventional case series study reviewed the medical records of 91 AS patients with uveitis. Results: The characteristics of AS-associated uveitis included male preponderance (70%), average onset in the fourth decade, unilateral manifestation (87.9%), and vitreous involvement or retinal vascular leakage (36.3%). All patients had acute anterior uveitis. The best corrected visual acuity in logMAR improved from 0.8 ± 0.3 to 0.1 ± 0.2. The use of biologic agents was the only significant factor in the multivariate analysis. Patients with vitreous involvement/retinal vascular leakage were more likely to use systemic/peribulbar steroids for inflammation control, and achieved equally favorable visual outcome as in those without vitreous involvement/retinal vascular leakage. Conclusion: The clinical characteristics and profile of visual prognostic factors suggest an association between the severity of ocular inflammation and systemic disease.

Original languageEnglish
Pages (from-to)64-69
Number of pages6
JournalOcular Immunology and Inflammation
Volume27
Issue number1
DOIs
Publication statusPublished - 2019 Jan 2

Fingerprint

Retinal Vessels
Ankylosing Spondylitis
Uveitis
Inflammation
Anterior Uveitis
Biological Factors
Visual Acuity
Medical Records
Multivariate Analysis
Steroids

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Ophthalmology

Cite this

Lee, Ji Hwan ; Choi, Moonjung ; Rim, Tyler Hyung Taek ; Lee, Sung Chul ; Lee, Christopher Seungkyu. / Clinical Characteristics and Prognostic Factors in Ankylosing Spondylitis Associated Uveitis. In: Ocular Immunology and Inflammation. 2019 ; Vol. 27, No. 1. pp. 64-69.
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Clinical Characteristics and Prognostic Factors in Ankylosing Spondylitis Associated Uveitis. / Lee, Ji Hwan; Choi, Moonjung; Rim, Tyler Hyung Taek; Lee, Sung Chul; Lee, Christopher Seungkyu.

In: Ocular Immunology and Inflammation, Vol. 27, No. 1, 02.01.2019, p. 64-69.

Research output: Contribution to journalArticle

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