TY - JOUR
T1 - Clinical characteristics of constrictive pericarditis diagnosed by echo-Doppler technique in Korea
AU - Yang, Hyun Suk
AU - Song, Jae Kwan
AU - Song, Jong Min
AU - Kang, Duk Hyun
AU - Lee, Cheol Whan
AU - Nam, Gi Byoung
AU - Choi, Kee Joon
AU - Kim, You Ho
AU - Hong, Myeong Ki
AU - Kim, Jae Joong
AU - Park, Seong Wook
AU - Park, Seung Jung
AU - Song, Hyun
AU - Lee, Jae Won
AU - Song, Meong Gun
PY - 2001/10
Y1 - 2001/10
N2 - A retrospective analysis of clinical data of 71 patients with constrictive pericarditis (CP) diagnosed by echo-Doppler technique (mean age, 49±17) was done. In 27 patients (38%), the etiology was unknown, and the three most frequent identifiable causes were tuberculosis (23/71, 32%), cardiac surgery (8/71, 11%), and mediastinal irradiation (6/71, 9%). Pericardiectomy was performed in 35 patients (49%) with a surgical mortality of 6% (2/35), and 11 patients (15%, 11/ 71) showed complete resolution of constrictive physiology with medical treatment. Patients with transient CP were characterized by absence of pericardial calcification, shorter symptom duration, and higher incidence of fever, weight loss, and tuberculosis. The 5-yr survival rates of patients with transient CP and those undergoing pericardiectomy were 100% and 85±6%, respectively, which were significantly higher than that of patients without undergoing pericardiectomy (33±17%, p=0.0083). Mediastinal irradiation, higher functional class, low voltage in ECG, low serum albumin, and old age were the independent variables associated with a higher mortality. Tuberculosis is still the most important etiology of CP in Korea, and not infrequently, it may cause transient CP. Early diagnosis and decision-making using follow-up echocardiography are crucial to improve the prognosis of patients with CP.
AB - A retrospective analysis of clinical data of 71 patients with constrictive pericarditis (CP) diagnosed by echo-Doppler technique (mean age, 49±17) was done. In 27 patients (38%), the etiology was unknown, and the three most frequent identifiable causes were tuberculosis (23/71, 32%), cardiac surgery (8/71, 11%), and mediastinal irradiation (6/71, 9%). Pericardiectomy was performed in 35 patients (49%) with a surgical mortality of 6% (2/35), and 11 patients (15%, 11/ 71) showed complete resolution of constrictive physiology with medical treatment. Patients with transient CP were characterized by absence of pericardial calcification, shorter symptom duration, and higher incidence of fever, weight loss, and tuberculosis. The 5-yr survival rates of patients with transient CP and those undergoing pericardiectomy were 100% and 85±6%, respectively, which were significantly higher than that of patients without undergoing pericardiectomy (33±17%, p=0.0083). Mediastinal irradiation, higher functional class, low voltage in ECG, low serum albumin, and old age were the independent variables associated with a higher mortality. Tuberculosis is still the most important etiology of CP in Korea, and not infrequently, it may cause transient CP. Early diagnosis and decision-making using follow-up echocardiography are crucial to improve the prognosis of patients with CP.
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U2 - 10.3346/jkms.2001.16.5.558
DO - 10.3346/jkms.2001.16.5.558
M3 - Article
C2 - 11641523
AN - SCOPUS:0035487443
VL - 16
SP - 558
EP - 566
JO - Journal of Korean Medical Science
JF - Journal of Korean Medical Science
SN - 1011-8934
IS - 5
ER -