Clinical characteristics of endogenous Klebsiella pneumoniae endophthalmitis: a 13-year experience

Ji Hwan Lee, Hee Suk Kim, Suk Ho Byeon, Sung Soo Kim, Hyoung Jun Koh, Sung Chul Lee, Christopher Seungkyu Lee

Research output: Contribution to journalArticlepeer-review


Purpose: This study aimed to investigate the clinical features and risk factors for poor visual outcomes in patients with endogenous Klebsiella pneumoniae endophthalmitis (EKE). Methods: This retrospective interventional case series reviewed the medical records of 17 patients (21 eyes) with EKE from January 2007 to December 2019. Clinical findings, treatments, visual outcomes, and potential prognostic factors were evaluated. Results: The mean age of the patients was 55.9 years and 13 patients (76.5%) were males. Diabetes (23.5%) was the most commonly associated systemic disease and liver abscess (70.6%) was the major infection source. Poor initial visual acuity worse than counting fingers was significantly associated with poor final visual outcome (p = 0.003). In this study, adjunctive intravitreal dexamethasone injection and primary vitrectomy were not associated with final visual outcome. Secondary enucleation/evisceration was performed in 14.3%. Conclusions: EKE usually has a poor visual prognosis, and early diagnosis with fair initial visual acuity would be crucial in saving vision.

Original languageEnglish
Pages (from-to)2533-2539
Number of pages7
JournalInternational Ophthalmology
Issue number8
Publication statusPublished - 2022 Aug

Bibliographical note

Funding Information:
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) under 2019R1A2C2002393 (C.S.L.). The funding organization had no role in the design or conduct of this research.

Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Nature B.V.

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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