TY - JOUR
T1 - Clinical effects of hypertension on the mortality of patients with acute myocardial infarction
AU - Kang, Dong Goo
AU - Jeong, Myung Ho
AU - Ahn, Yongkeun
AU - Chae, Shung Chull
AU - Hur, Seung Ho
AU - Hong, Taek Jong
AU - Kim, Young Jo
AU - Seong, In Whan
AU - Chae, Jei Keon
AU - Rhew, Jay Young
AU - Chae, In Ho
AU - Cho, Myeong Chan
AU - Bae, Jang Ho
AU - Rha, Seung Woon
AU - Kim, Chong Jin
AU - Jang, Yang Soo
AU - Yoon, Junghan
AU - Seung, Ki Bae
AU - Park, Seung Jung
PY - 2009/10
Y1 - 2009/10
N2 - The incidence of ischemic heart disease has been increased rapidly in Korea. How-ever, the clinical effects of antecedent hypertension on acute myocardial infarction have not been identified. We assessed the relationship between antecedent hypertension and clinical outcomes in 7,784 patients with acute myocardial infarction in the Korea Acute Myocardial Infarction Registry during one-year follow-up. Diabetes mellitus, hyperlipidemia, cerebrovascular disease, heart failure, and peripheral artery disease were more prevalent in hypertensives (n=3,775) than nonhypertensives (n=4,009). During hospitalization, hypertensive patients suffered from acute renal failure, shock, and cerebrovascular event more frequently than in nonhypertensives. During follow-up of one-year, the incidence of major adverse cardiac events was higher in hypertensives. In multi-variate adjustment, old age, Killip class ≥III, left ventricular ejection fraction <45%, systolic blood pressure <90 mmHg on admission, post procedural TIMI flow grade ≤2, female sex, and history of hypertension were independent predictors for in-hospital mortality. However antecedent hypertension was not significantly associated with one-year mortality. Hypertension at the time of acute myocardial infarction is associated with an increased rate of in-hospital mortality.
AB - The incidence of ischemic heart disease has been increased rapidly in Korea. How-ever, the clinical effects of antecedent hypertension on acute myocardial infarction have not been identified. We assessed the relationship between antecedent hypertension and clinical outcomes in 7,784 patients with acute myocardial infarction in the Korea Acute Myocardial Infarction Registry during one-year follow-up. Diabetes mellitus, hyperlipidemia, cerebrovascular disease, heart failure, and peripheral artery disease were more prevalent in hypertensives (n=3,775) than nonhypertensives (n=4,009). During hospitalization, hypertensive patients suffered from acute renal failure, shock, and cerebrovascular event more frequently than in nonhypertensives. During follow-up of one-year, the incidence of major adverse cardiac events was higher in hypertensives. In multi-variate adjustment, old age, Killip class ≥III, left ventricular ejection fraction <45%, systolic blood pressure <90 mmHg on admission, post procedural TIMI flow grade ≤2, female sex, and history of hypertension were independent predictors for in-hospital mortality. However antecedent hypertension was not significantly associated with one-year mortality. Hypertension at the time of acute myocardial infarction is associated with an increased rate of in-hospital mortality.
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U2 - 10.3346/jkms.2009.24.5.800
DO - 10.3346/jkms.2009.24.5.800
M3 - Article
C2 - 19794974
AN - SCOPUS:75349112192
VL - 24
SP - 800
EP - 806
JO - Journal of Korean Medical Science
JF - Journal of Korean Medical Science
SN - 1011-8934
IS - 5
ER -