Clinical efficacy of nonsurgical treatment of Crohn's disease-related intraabdominal abscess

Duk Hwan Kim, JaeHee Cheon, Chang Mo Moon, Jae Jun Park, Song Yi Han, Eun Soo Kim, Moon Jae Chung, Jin Ha Lee, Min Kyu Jung, Soo Hyun Lee, Jung Woo Son, Tae Il Kim, Won Ho Kim

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Abstract

BACKGROUND/AIMS: This study was conducted to compare the clinical efficacy between surgical and nonsurgical treatments for patients with Crohn's disease-related intraabdominal abscess. METHODS: A retrospective review of medical records was performed for patients admitted to a single institution due to Crohn's disease-related intraabdominal abscess from February, 1996 to February, 2008. Clinical outcomes were compared between surgical and nonsurgical groups in terms of treatment responses and recurrences. RESULTS: A total of 47 episodes of intraabdominal abscesses in 43 patients (12.7%) were identified from 339 patients with Crohn's disease. Of these, initially, 18 cases (38.3%) underwent surgical treatment and 29 (61.7%) were treated medically (antibiotic treatments with or without percutaneous drainage). The overall treatment response rates of surgical and nonsurgical group were 100% versus 89.7% (p=0.11) and recurrence rates were 27.8% versus 30.8% (p=1.00). Three patients in nonsurgical group (10.3%) showed no response to therapy and ultimately received surgical drainages. The median length of hospitalization in nonsurgical group was shorter than in surgical group (12 and 29.5 days, respectively. p=0.02). CONCLUSIONS: Nonsurgical treatment might be as effective as surgical treatment for the treatment of Crohn's disease-related intraabdominal abscess, especially considering shorter hospital stay.

Original languageEnglish
Pages (from-to)29-35
Number of pages7
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume53
Issue number1
Publication statusPublished - 2009 Jan 1

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All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kim, D. H., Cheon, J., Moon, C. M., Park, J. J., Han, S. Y., Kim, E. S., Chung, M. J., Lee, J. H., Jung, M. K., Lee, S. H., Son, J. W., Kim, T. I., & Kim, W. H. (2009). Clinical efficacy of nonsurgical treatment of Crohn's disease-related intraabdominal abscess. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 53(1), 29-35.