Objective: To evaluate the feasibility of synthetic magnetic resonance imaging (MRI) compared to conventional MRI for the diagnosis of internal derangements of the knee at 3T. Materials and Methods: Following Institutional Review Board approval, image sets of conventional and synthetic MRI in 39 patients were included. Two musculoskeletal radiologists compared the image sets and qualitatively analyzed the images. Subjective image quality was assessed using a four-grade scale. Interobserver agreement and intersequence agreement between conventional and synthetic images for cartilage lesions, tears of the cruciate ligament, and tears of the meniscus were independently assessed using Kappa statistics. In patients who underwent arthroscopy (n = 8), the sensitivity, specificity, and accuracy for evaluated internal structures were calculated using arthroscopic findings as the gold standard. Results: There was no statistically significant difference in image quality (p = 0.90). Interobserver agreement (κ = 0.649− 0.981) and intersequence agreement (κ = 0.794−0.938) were nearly perfect for all evaluated structures. The sensitivity, specificity, and accuracy for detecting cartilage lesions (sensitivity, 63.6% vs. 54.6−63.6%; specificity, 91.9% vs. 91.9%; accuracy, 83.3−85.4% vs. 83.3−85.4%) and tears of the cruciate ligament (sensitivity, specificity, accuracy, 100% vs. 100%) and meniscus (sensitivity, 50.0–62.5% vs. 62.5%; specificity, 100% vs. 87.5−100%; accuracy, 83.3−85.4% vs. 83.3−85.4%) were similar between the two MRI methods. Conclusion: Conventional and synthetic MRI showed substantial to almost perfect degree of agreement for the assessment of internal derangement of knee joints. Synthetic MRI may be feasible in the diagnosis of internal derangements of the knee.
Bibliographical noteFunding Information:
This work was supported by a National Research Foundation (NRF) grant funded by the Korea government, Ministry of Science, ICT & Future Planning (MSIP, 2015R1A2A1A05001887).
Received December 21, 2016; accepted after revision August 12, 2017. This work was supported by a National Research Foundation (NRF) grant funded by the Korea government, Ministry of Science, ICT & Future Planning (MSIP, 2015R1A2A1A05001887). Corresponding author: Young Han Lee, MD, Department of Radiology, Research Institute of Radiological Science, YUHS-KRIBB Medical Convergence Research Institute, and Severance Biomedical Science Institute, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. • Tel: (822) 2228-7420 • Fax: (822) 393-3035 • E-mail: firstname.lastname@example.org *Current address: Department of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan 48108, Korea. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging