Clinical features and surgical outcomes of primary cauda equina tumours

DongAh Shin, Joong Won Yang, Seong Yi, Yoon Ha, Do Heum Yoon, Keung Nyun Kim

Research output: Contribution to journalArticle

Abstract

Background: To identify clinical features, radiological findings and surgical outcomes of primary cauda equina tumours. Methods: A consecutive series of 64 operations in 60 patients with primary cauda equina tumours from April 1999 to May 2009 at one institution comprised the study. The cases were divided into tumours of neural sheath origin (TNS, n = 48) and tumours of non-neural sheath origin (TNNS, n = 22). We analysed pain intensity, neurological abnormalities, MRI findings, surgical extent and functional outcome. Results: The TNS group showed more leg pain (76 % vs. 44 %, p = 0.019) with higher intensity (6.1 ± 1.5 vs. 4.6 ± 1.9, p = 0.04). Motor weakness and bladder dysfunction were more common in the TNNS group (p = 0.028 and p = 0.00 in each). Flow voids of MRI were more frequently observed in TNNS (50 % vs. 4 %, p = 0.01). The TNS group achieved total removal in all operations compared with total removal in 77 % in the TNNS group (p = 0.001). The TNNS group showed higher recurrence rates (18 % vs. 0 %, p = 0.009). The TNS group showed higher improvement of JOA scores postoperatively (p = 0.049). Surgical complications were observed less frequently in the TNS group (19 % vs. 78 %, p = 0.000). Conclusions: TNS differs from TNNS by causing more frequent leg pain, higher pain intensity and more frequent flow voids. TNS has better surgical outcomes than TNNS in terms of higher rates of total removal, fewer surgical complications, better functional outcomes and less recurrence.

Original languageEnglish
Pages (from-to)1911-1916
Number of pages6
JournalActa Neurochirurgica
Volume155
Issue number10
DOIs
Publication statusPublished - 2013 Oct 1

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Cauda Equina
Neoplasms
Pain
Leg
Recurrence
2-(4-toluidino)-6-naphthalenesulfonic acid
Urinary Bladder

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Surgery

Cite this

Shin, DongAh ; Yang, Joong Won ; Yi, Seong ; Ha, Yoon ; Yoon, Do Heum ; Kim, Keung Nyun. / Clinical features and surgical outcomes of primary cauda equina tumours. In: Acta Neurochirurgica. 2013 ; Vol. 155, No. 10. pp. 1911-1916.
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abstract = "Background: To identify clinical features, radiological findings and surgical outcomes of primary cauda equina tumours. Methods: A consecutive series of 64 operations in 60 patients with primary cauda equina tumours from April 1999 to May 2009 at one institution comprised the study. The cases were divided into tumours of neural sheath origin (TNS, n = 48) and tumours of non-neural sheath origin (TNNS, n = 22). We analysed pain intensity, neurological abnormalities, MRI findings, surgical extent and functional outcome. Results: The TNS group showed more leg pain (76 {\%} vs. 44 {\%}, p = 0.019) with higher intensity (6.1 ± 1.5 vs. 4.6 ± 1.9, p = 0.04). Motor weakness and bladder dysfunction were more common in the TNNS group (p = 0.028 and p = 0.00 in each). Flow voids of MRI were more frequently observed in TNNS (50 {\%} vs. 4 {\%}, p = 0.01). The TNS group achieved total removal in all operations compared with total removal in 77 {\%} in the TNNS group (p = 0.001). The TNNS group showed higher recurrence rates (18 {\%} vs. 0 {\%}, p = 0.009). The TNS group showed higher improvement of JOA scores postoperatively (p = 0.049). Surgical complications were observed less frequently in the TNS group (19 {\%} vs. 78 {\%}, p = 0.000). Conclusions: TNS differs from TNNS by causing more frequent leg pain, higher pain intensity and more frequent flow voids. TNS has better surgical outcomes than TNNS in terms of higher rates of total removal, fewer surgical complications, better functional outcomes and less recurrence.",
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Clinical features and surgical outcomes of primary cauda equina tumours. / Shin, DongAh; Yang, Joong Won; Yi, Seong; Ha, Yoon; Yoon, Do Heum; Kim, Keung Nyun.

In: Acta Neurochirurgica, Vol. 155, No. 10, 01.10.2013, p. 1911-1916.

Research output: Contribution to journalArticle

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AU - Yang, Joong Won

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AU - Ha, Yoon

AU - Yoon, Do Heum

AU - Kim, Keung Nyun

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